Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | ATF4 | P18848 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27865576 | 0.82 | RECQL (0.50) | MEN1KMT2AALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL4689285 | 0.82 | MEN1 (0.45) | MEN1KMT2AALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL2171671 | 0.71 | L3MBTL1 (0.68) | MEN1KMT2AALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL28724159 | 0.69 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2CYP1A2CYP3A4TSHR | |
| SCHEMBL24696398 | 0.68 | PPARA (0.60) | MEN1KMT2AALDH1A1SMN1; SMN2ABCB11 | |
| SCHEMBL9799923 | 0.68 | KMT2A (0.63) | KMT2AALDH1A1SMN1; SMN2ABCB11CYP1A2 | |
| SCHEMBL197418 | 0.68 | KMT2A (0.63) | KMT2AALDH1A1SMN1; SMN2ABCB11CYP1A2 | |
| SCHEMBL4621713 | 0.68 | KMT2A (0.77) | MEN1KMT2AALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL16392373 | 0.68 | KMT2A (0.47) | MEN1KMT2AALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL1010862 | 0.67 | PPARA (0.38) | MEN1KMT2AALDH1A1L3MBTL1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111777597-A | Anti-hepatic fibrosis compound, preparation method and application | 江西省医学科学院 | 2020-10-16 | — | — | CN | claimed |
| CN-110627774-A | Anti-hepatic fibrosis compound, preparation method and application | 江西省医学科学院 | 2019-12-31 | — | — | CN | claimed |
| CN-111777597-A | Anti-hepatic fibrosis compound, preparation method and application | 江西省医学科学院 | 2020-10-16 | — | — | CN | disclosed |
| CN-110627774-A | Anti-hepatic fibrosis compound, preparation method and application | 江西省医学科学院 | 2019-12-31 | — | — | CN | disclosed |