Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ATF4 | P18848 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28724159 | 0.83 | ALDH1A1 (0.42) | ALDH1A1CYP1A2CYP3A4TSHRPMP22 | |
| SCHEMBL1117020 | 0.83 | CA1 (0.52) | KMT2AALDH1A1L3MBTL1SMN1; SMN2CYP2C19 | |
| SCHEMBL28339055 | 0.82 | MEN1 (0.46) | MEN1KMT2AALDH1A1L3MBTL1CYP1A2 | |
| SCHEMBL4540135 | 0.81 | RECQL (0.53) | MEN1KMT2AALDH1A1L3MBTL1HPGD | |
| SCHEMBL8495864 | 0.80 | OGG1 (0.50) | MEN1KMT2AALDH1A1L3MBTL1KDM4E | |
| SCHEMBL16392373 | 0.79 | KMT2A (0.47) | MEN1KMT2AALDH1A1L3MBTL1CYP1A2 | |
| SCHEMBL1116917 | 0.77 | ALDH1A1 (0.54) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL27816666 | 0.76 | TSHR (0.52) | MEN1KMT2AALDH1A1L3MBTL1CYP1A2 | |
| SCHEMBL4599074 | 0.74 | ALDH1A1 (0.42) | MEN1KMT2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL2171671 | 0.74 | L3MBTL1 (0.68) | MEN1KMT2AALDH1A1L3MBTL1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1496838-A4 | SUBSTITUTED AMIDES | MERCK & CO INC (US) | 2008-07-02 | — | — | EP | claimed |
| EP-1496838-A2 | SUBSTITUTED AMIDES | Merck & Co., Inc. (US) | 2005-01-19 | — | — | EP | claimed |
| WO-2003077847-A2 | SUBSTITUTED AMIDES | MERCK & CO., INC. (US) | 2003-09-25 | — | — | WO | claimed |
| EP-0008973-B1 | A PROCESS FOR PREPARING PHENOXYLACTIC ACIDS AND THEIR DERIVATIVES, AND PRODUCTS OBTAINED | SUCRERIES DU SOISSONNAIS ET COMPAGNIE SUCRIERE Société anonyme dite: (FR) | 1982-09-29 | — | — | EP | claimed |
| EP-0008973-A2 | A process for preparing phenoxylactic acids and their derivatives, and products obtained | SUCRERIES DU SOISSONNAIS ET COMPAGNIE SUCRIERE Société anonyme dite: (FR) | 1980-03-19 | — | — | EP | claimed |