SCHEMBL28342168

SCHEMBL28342168

O=C(CCCCCCC(=O)ON1C(=O)CCC1=O)OCCO

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.40
MGLL Q99685 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
KMT2A Q03164 1/20 0.35
PRKCA P17252 7/20 0.35
DNM1 Q05193 1/20 0.34
HPGD P15428 1/20 0.33
HTT P42858 1/20 0.33
ALOX12 P18054 1/20 0.33
EPHX2 P34913 1/20 0.32
ALDH1A1 P00352 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
PSMB8 P28062 1/20 0.31
PSMB5 P28074 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28192296 1.00 DGKA (0.40) DGKAMGLLSMN1; SMN2KMT2APRKCA
SCHEMBL22712661 0.98 MGLL (0.37) DGKAMGLLSMN1; SMN2KMT2APRKCA
SCHEMBL310052 0.95 MGLL (0.37) DGKAMGLLSMN1; SMN2KMT2APRKCA
SCHEMBL1869815 0.92 ADRA2A (0.33) MGLLALOX12PSMB8PSMB5
SCHEMBL4893239 0.88 MGLL (0.33) DGKAMGLLSMN1; SMN2KMT2AALOX12
SCHEMBL17637586 0.88 DGKA (0.43) DGKASMN1; SMN2KMT2APRKCADNM1
SCHEMBL15760609 0.88 PRKCA (0.33) DGKAMGLLSMN1; SMN2KMT2APRKCA
SCHEMBL16303081 0.87 SMN1; SMN2 (0.38) SMN1; SMN2KMT2APRKCAHPGDHTT
SCHEMBL7877323 0.87 SMN1; SMN2 (0.38) SMN1; SMN2KMT2APRKCAHPGDHTT
SCHEMBL27050999 0.87 SMN1; SMN2 (0.38) SMN1; SMN2KMT2APRKCAHPGDHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116271188-A Medical hydrogel, preparation method and application thereof in preparation of vascular leakage sealing agent 赛克赛斯生物科技股份有限公司 2023-06-23 CN claimed
CN-113827766-B Drug-loaded surgical sealant and preparation method and application thereof 赛克赛斯生物科技股份有限公司 2022-05-24 CN claimed
CN-113827766-A Drug-loaded surgical sealant and preparation method and application thereof 赛克赛斯生物科技股份有限公司 2021-12-24 CN claimed
CN-113813440-A Hydrogel material with adjustable biological adhesion and preparation method and application thereof 赛克赛斯生物科技股份有限公司 2021-12-21 CN claimed
CN-110643057-A Application of polyethylene glycol activated ester in preparation of low-swelling hydrogel and low-swelling hydrogel comprising same 赛克赛斯生物科技股份有限公司 2020-01-03 CN claimed
CN-113813440-B Bioadhesive adjustable hydrogel material and preparation method and application thereof 赛克赛斯生物科技股份有限公司 2023-08-04 CN disclosed
CN-116271188-A Medical hydrogel, preparation method and application thereof in preparation of vascular leakage sealing agent 赛克赛斯生物科技股份有限公司 2023-06-23 CN disclosed
CN-113827766-B Drug-loaded surgical sealant and preparation method and application thereof 赛克赛斯生物科技股份有限公司 2022-05-24 CN disclosed
CN-110643057-B Application of polyethylene glycol activated ester in preparation of low-swelling hydrogel and low-swelling hydrogel comprising polyethylene glycol activated ester 赛克赛斯生物科技股份有限公司 2022-05-17 CN disclosed
CN-113827766-A Drug-loaded surgical sealant and preparation method and application thereof 赛克赛斯生物科技股份有限公司 2021-12-24 CN disclosed
CN-113813440-A Hydrogel material with adjustable biological adhesion and preparation method and application thereof 赛克赛斯生物科技股份有限公司 2021-12-21 CN disclosed
CN-110643057-A Application of polyethylene glycol activated ester in preparation of low-swelling hydrogel and low-swelling hydrogel comprising same 赛克赛斯生物科技股份有限公司 2020-01-03 CN disclosed