SCHEMBL1869815

SCHEMBL1869815

O=C(CCC(=O)ON1C(=O)CCC1=O)OCCO

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 1/20 0.33
ADRA1A P35348 1/20 0.33
PSMB8 P28062 1/20 0.33
PSMB5 P28074 1/20 0.33
MGLL Q99685 1/20 0.33
MAPT P10636 1/20 0.32
BLM P54132 1/20 0.32
ALOX12 P18054 1/20 0.32
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22712661 0.93 MGLL (0.37) PSMB8PSMB5MGLLMAPTALOX12
SCHEMBL310052 0.93 MGLL (0.37) PSMB8PSMB5MGLLMAPTALOX12
2-Methoxyethanol SCHEMBL29386411 0.92 HPGD (0.35) ADRA2AADRA1APSMB8PSMB5MGLL
SCHEMBL28342168 0.92 DGKA (0.40) PSMB8PSMB5MGLLALOX12
SCHEMBL28192296 0.92 DGKA (0.40) PSMB8PSMB5MGLLALOX12
SCHEMBL141048 0.91 ADRA2A (0.36) ADRA2AADRA1APSMB8PSMB5MGLL
SCHEMBL28680314 0.91 EPHX2 (0.34) ADRA2AADRA1APSMB8PSMB5TDP1
SCHEMBL15760611 0.90 PRKCA (0.33) ADRA2AADRA1APSMB8PSMB5MAPT
SCHEMBL4908861 0.89
Ethylene Glycol SCHEMBL999673 0.87 PSMB8 (0.36) PSMB8PSMB5MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114099784-A Injection type skin filling composition and preparation method and application thereof 四川兴科蓉药业有限责任公司 2022-03-01 CN claimed
CN-108601819-A Amelioration of systemic sclerosis with death receptor agonists 约翰霍普金斯大学 2018-09-28 CN claimed
CN-101056595-B Compositions, systems and methods for treatment of defects in blood vessels MICROVENTION, INC. (US) 2012-02-08 CN claimed
EP-1578450-A4 AMPLIFICATION OF BIOTIN-MEDIATED TARGETING ACCESS PHARMACEUTICALS AUSTRAL (AU) 2009-06-17 EP claimed
EP-1824414-A2 COMPOSITIONS, SYSTEMS AND METHODS FOR TREATMENT OF DEFECTS IN BLOOD VESSELS MicroVention, Inc. (US) 2007-08-29 EP claimed
US-7201918-B2 Compositions, systems and methods for treatment of defects in blood vessels MICROVENTION, INC. (US) 2007-04-10 US claimed
EP-1585758-A4 PEPTIDES HAVING PROTECTED AMINES OF UNTARGETED SITES, METHODS FOR PRODUCTION THEREOF AND OF SPECIFICALLY CONJUGATED PEG PEPTIDES USING THE SAME PEGSPHERE CO LTD (KR) 2006-06-07 EP claimed
WO-2006055690-A2 COMPOSITIONS, SYSTEMS AND METHODS FOR TREATMENT OF DEFECTS IN BLOOD VESSELS MICROVENTION, INC. (US) 2006-05-26 WO claimed
US-20060105014-A1 Compositions, systems and methods for treatment of defects in blood vessels MICROVENTION, INC. (US) 2006-05-18 US claimed
US-20060063914-A1 specifically conjugating polyethylene glycol to targeted sites of the synthetic peptides; pegylation; synthetic peptides having selectively protected amines of untargeted sites PEGSPHERE CO., LTD. (KR) 2006-03-23 US claimed
EP-1585758-A1 PEPTIDES HAVING PROTECTED AMINES OF UNTARGETED SITES, METHODS FOR PRODUCTION THEREOF AND OF SPECIFICALLY CONJUGATED PEG PEPTIDES USING THE SAME PEGSPHERE Co., Ltd. (KR) 2005-10-19 EP claimed
EP-1578450-A1 AMPLIFICATION OF BIOTIN-MEDIATED TARGETING Access Pharmaceuticals Australia Pty Ltd (AU) 2005-09-28 EP claimed
WO-2004065412-A1 PEPTIDES HAVING PROTECTED AMINES OF UNTARGETED SITES, METHODS FOR PRODUCTION THEREOF AND OF SPECIFICALLY CONJUGATED PEG PEPTIDES USING THE SAME PEGSPHERE CO., LTD. (KR) 2004-08-05 WO claimed
WO-2004045647-A1 AMPLIFICATION OF BIOTIN-MEDIATED TARGETING ACCESS PHARMACEUTICALS AUSTRALIA PTY LTD (AU) 2004-06-03 WO claimed
CN-118043084-A Compositions and methods for metal-containing formulations capable of modulating immune responses 密执安大学评议会 2024-05-14 CN disclosed
CN-118043068-A RNA vaccine 阿克丘勒斯治疗公司 2024-05-14 CN disclosed
WO-2024094027-A1 BLOCKING SEQUENCE, KIT THEREOF, AND METHOD FOR USING SAME 深圳鸿生生物科技有限公司 2024-05-10 WO disclosed
EP-0067029-B1 OXYGEN CARRIER AJINOMOTO CO., INC. (JP) 1986-04-30 EP disclosed
US-4412989-A POLYOXYALKYLENE GLYCOL COUPLED TO A HEMOGLOBIN OR HEMOGLOBIN DERIVATIVE AJINOMOTO COMPANY INCORPORATED (JP) 1983-11-01 US disclosed
EP-0067029-A2 Oxygen carrier AJINOMOTO CO., INC. (JP) 1982-12-15 EP disclosed