Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 8/20 | 0.83 |
| ▸ | CES1 | P23141 | 6/20 | 0.83 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.59 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.53 |
| ▸ | KIF11 | P52732 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 2/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.52 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3172262 | 0.91 | CES2 (1.00) | CES2CES1SRD5A2TSHRGSK3B | |
| SCHEMBL1781341 | 0.87 | SRD5A2 (0.77) | CES2CES1NPC1RAB9ASRD5A2 | |
| SCHEMBL3058646 | 0.84 | CES2 (0.78) | CES2CES1NPC1RAB9ASRD5A2 | |
| SCHEMBL16340031 | 0.83 | CES2 (0.60) | CES2CES1NPC1RAB9AP2RX1 | |
| SCHEMBL20010796 | 0.83 | CES2 (0.83) | CES2CES1SRD5A2CYP1A1CYP1B1 | |
| SCHEMBL160203 | 0.82 | ALDH1A1 (0.59) | CES2CES1NPC1RAB9ASRD5A2 | |
| SCHEMBL4848676 | 0.82 | CES2 (0.89) | CES2CES1RAB9ASRD5A2MAOB | |
| SCHEMBL779220 | 0.82 | NPC1 (0.56) | CES2CES1NPC1RAB9ASRD5A2 | |
| SCHEMBL22130998 | 0.82 | PTPN1 (0.71) | CES2CES1NPC1RAB9ASRD5A2 | |
| SCHEMBL13019489 | 0.82 | SRD5A2 (0.69) | CES2CES1NPC1RAB9ASRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230278965-A1 | NOVEL CARBONOHYDRAZONOYL DICYANIDE COMPOUNDS COMPRISING 2 OR MORE ARYL OR HETEROARYL CONNECTED VIA LINKER AND USE THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2023-09-07 | — | — | US | disclosed |
| CN-102906215-B | Photochromic material | MITSUBISHI GAS CHEMICAL CO | 2014-11-05 | — | — | CN | disclosed |
| CN-102906215-A | Photochromic material | MITSUBISHI GAS CHEMICAL CO | 2013-01-30 | — | — | CN | disclosed |
| CN-102877022-A | Evaporation mask, method of manufacturing evaporation mask, electronic device, and method of manufacturing electronic device | SONY CORP | 2013-01-16 | — | — | CN | disclosed |
| US-7728014-B2 | Heteroaromatic compounds having sphingosine-1-phosphate (S1P) receptor agonist biological activity | ALLERGAN, INC. | 2010-06-01 | — | — | US | disclosed |
| US-7728014-B2 | Heteroaromatic compounds having sphingosine-1-phosphate (S1P) receptor agonist biological activity | ALLERGAN, INC. | 2010-06-01 | — | — | US | disclosed |
| EP-2066633-A1 | HETEROAROMATIC COMPOUNDS HAVING SPHINGOSINE-1-PHOSPHATE (S1P) RECEPTOR AGONIST AND/OR ANTAGONIST BIOLOGICAL ACTIVITY | Allergan, Inc. (US) | 2009-06-10 | — | — | EP | disclosed |
| EP-2064183-A2 | HETEROAROMATIC COMPOUNDS HAVING SPHINGOSINE-1-PHOSPHATE (S1P) RECEPTOR AGONIST BIOLOGICAL ACTIVITY | Allergan, Inc. (US) | 2009-06-03 | — | — | EP | disclosed |
| US-7439360-B2 | Vanilloid receptor ligands and their use in treatments | AMGEN INC. (US) | 2008-10-21 | — | — | US | disclosed |
| US-7439360-B2 | Vanilloid receptor ligands and their use in treatments | AMGEN INC. (US) | 2008-10-21 | — | — | US | disclosed |
| US-20070054902-A1 | Isoxazole derivatives as peroxisome proliferator-activated receptors agonists | SHIONOGI & CO., LTD. (JP) | 2007-03-08 | — | — | US | disclosed |
| EP-1690538-A1 | ISOXAZOLE DERIVATIVE HAVING AGONISTIC ACTIVITY AGAINST PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR | SHIONOGI & CO., LTD. (JP) | 2006-08-16 | — | — | EP | disclosed |
| WO-2006044527-A1 | IMIDAZOLE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | AMGEN INC. (US) | 2006-04-27 | — | — | WO | disclosed |
| US-20060084640-A1 | Vanilloid receptor ligands and their use in treatments | AMGEN INC. | 2006-04-20 | — | — | US | disclosed |
| EP-0920314-B1 | NON-PEPTIDE G-CSF MIMETICS | SMITHKLINE BEECHAM CORP (US) | 2003-08-27 | — | — | EP | disclosed |
| EP-0920314-A4 | NON-PEPTIDE G-CSF MIMETICS | SMITHKLINE BEECHAM CORP (US) | 2001-08-16 | — | — | EP | disclosed |
| US-5981551-A | GRANULOCYTE COLONY-STIMULATING FACTOR MIMETICS; TREATMENT OF NEUTROPENIA | SMITHKLINE BEECHAM CORPORATION (US) | 1999-11-09 | — | — | US | disclosed |
| EP-0920314-A1 | NON-PEPTIDE G-CSF MIMETICS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-06-09 | — | — | EP | disclosed |
| WO-1997044033-A1 | NON-PEPTIDE G-CSF MIMETICS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-11-27 | — | — | WO | disclosed |
| US-4009022-A | Selective antagonists for triazine herbicides | ROHM AND HAAS COMPANY (US) | 1977-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230278965-A1 | NOVEL CARBONOHYDRAZONOYL DICYANIDE COMPOUNDS COMPRISING 2 OR MORE ARYL OR HETEROARYL CONNECTED VIA LINKER AND USE THEREOF | AADAC, CBR3, MTCL3 | CES2 653/4885CES1 2895/4885NPC1 2328/4885 |
| US-20060084640-A1 | Vanilloid receptor ligands and their use in treatments | TRPV1, TRPV3, TRPV2 | CES2 4307/4885CES1 3870/4885NPC1 3093/4885 |
| US-20070054902-A1 | Isoxazole derivatives as peroxisome proliferator-activated receptors agonists | NR1H3, NR1H2, RXRA | CES2 1662/4885CES1 474/4885NPC1 1463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.