Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | POLA1 | P09884 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | DGKA | P23743 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.42 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14947259 | 0.87 | LMNA (0.53) | ZDHHC7PPARGL3MBTL1LMNATSHR | |
| SCHEMBL14947261 | 0.87 | LMNA (0.53) | ZDHHC7PPARGL3MBTL1LMNATSHR | |
| SCHEMBL4809286 | 0.84 | ZDHHC7 (0.57) | ZDHHC7PPARGL3MBTL1LMNATSHR | |
| SCHEMBL5052870 | 0.84 | ZDHHC7 (0.57) | ZDHHC7PPARGL3MBTL1LMNATSHR | |
| SCHEMBL9860092 | 0.83 | ZDHHC7 (0.56) | ZDHHC7PPARGL3MBTL1LMNATSHR | |
| SCHEMBL11456570 | 0.83 | ZDHHC7 (0.56) | ZDHHC7PPARGL3MBTL1LMNATSHR | |
| SCHEMBL5478205 | 0.81 | LMNA (0.49) | ZDHHC7PPARGL3MBTL1LMNATSHR | |
| SCHEMBL13182543 | 0.81 | PPARG (0.48) | ZDHHC7PPARGL3MBTL1LMNATSHR | |
| SCHEMBL4804388 | 0.81 | L3MBTL1 (0.48) | ZDHHC7PPARGL3MBTL1LMNATSHR | |
| SCHEMBL18124155 | 0.80 | ZDHHC7 (0.51) | ZDHHC7PPARGL3MBTL1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100228012-A1 | PENDANT FATTY ACID IMAGING AGENTS | MOLECULAR INSIGHT PHARMACEUTICALS, INC. | 2010-09-09 | — | — | US | disclosed |
| US-7556794-B2 | Pendant fatty acid imaging agents | MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) | 2009-07-07 | — | — | US | disclosed |
| US-20070128119-A1 | Pendant fatty acid imaging agents | MOLECULAR INSIGHT PHARMACEUTICALS, INC. | 2007-06-07 | — | — | US | disclosed |
| US-7179444-B2 | Pendant fatty acid imaging agents | MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) | 2007-02-20 | — | — | US | disclosed |
| EP-1490114-A1 | PENDANT FATTY ACID IMAGING AGENTS | Biostream, Inc. (US) | 2004-12-29 | — | — | EP | disclosed |
| US-20040081616-A1 | Pendant fatty acid imaging agents | BIOSTREAM, INC. | 2004-04-29 | — | — | US | disclosed |
| WO-2003084575-A1 | PENDANT FATTY ACID IMAGING AGENTS | BIOSTREAM, INC. (US) | 2003-10-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070128119-A1 | Pendant fatty acid imaging agents | FABP3, CPT1B, FABP1 | ZDHHC7 302/4885PPARG 171/4885L3MBTL1 4133/4885 |
| US-20100228012-A1 | PENDANT FATTY ACID IMAGING AGENTS | FABP3, CPT1B, FABP1 | ZDHHC7 302/4885PPARG 171/4885L3MBTL1 4133/4885 |
| US-20040081616-A1 | Pendant fatty acid imaging agents | FABP3, CPT1B, FABP1 | ZDHHC7 302/4885PPARG 171/4885L3MBTL1 4133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.