Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | FEN1 | P39748 | 7/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 6/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29280128 | 0.85 | PTPRC (0.43) | PTPRCPTPN1PTGS2PTGS1FEN1 | |
| SCHEMBL17184105 | 0.82 | MAOB (0.46) | PTPRCPTPN1PTGS2PTGS1FEN1 | |
| SCHEMBL28609832 | 0.78 | ALDH1A1 (0.40) | MAOBALDH1A1MAPK1BACE1TRPA1 | |
| SCHEMBL27253124 | 0.75 | PDK2 (0.41) | PTGS2PTGS1IDO1TDO2 | |
| SCHEMBL31315851 | 0.75 | NOTUM (0.45) | FEN1ALOX5APBACE1TRPA1 | |
| SCHEMBL4352639 | 0.75 | PARP1 (0.42) | PARP1IDO1TDO2 | |
| SCHEMBL8289012 | 0.74 | AKR1C3 (0.44) | PTPRCPTPN1PTGS2PTGS1FEN1 | |
| SCHEMBL30318876 | 0.74 | CRHBP (0.50) | ALDH1A1MAPK1IDO1TDO2 | |
| SCHEMBL456798 | 0.74 | CRHBP (0.50) | ALDH1A1MAPK1IDO1TDO2 | |
| SCHEMBL6950348 | 0.74 | PDK2 (0.48) | PTGS2PTGS1FEN1ALOX5APALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563120-B | alpha-D-galactoside inhibitors of galectins | 格莱克特生物技术公司 | 2022-12-02 | — | — | CN | disclosed |
| CN-110167939-B | Pyrrolo [2,3-c ] pyridine derivatives, preparation method and medical application thereof | 江苏豪森药业集团有限公司 | 2021-12-31 | — | — | CN | disclosed |
| CN-110198941-B | Pyrrolopyridine N-oxide derivative and preparation method and application thereof | 江苏豪森药业集团有限公司 | 2021-09-28 | — | — | CN | disclosed |
| CN-105916506-B | Quinazoline derivatives as inhibitors of TAM family kinases | 圣诺康生命科学公司 | 2020-01-07 | — | — | CN | disclosed |