Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.45 |
| ▸ | AR | P10275 | 5/20 | 0.44 |
| ▸ | PGR | P06401 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | RORB | Q92753 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7808032 | 0.86 | AR (0.58) | NOTUMARPGRMEN1LMNA | |
| SCHEMBL29280128 | 0.79 | PTPRC (0.43) | ALOX5APFEN1 | |
| SCHEMBL1042573 | 0.78 | NOTUM (0.50) | NOTUMARMEN1LMNAMAPT | |
| SCHEMBL28769063 | 0.75 | NOTUM (0.40) | NOTUMARPGRMEN1LMNA | |
| SCHEMBL6187171 | 0.75 | BCAT2 (0.50) | NOTUMMEN1LMNAMAPTKMT2A | |
| SCHEMBL28344391 | 0.75 | PTPRC (0.40) | TRPA1BACE1ALOX5APFEN1 | |
| SCHEMBL29683882 | 0.73 | PDK2 (0.46) | NOTUM | |
| SCHEMBL28609832 | 0.71 | ALDH1A1 (0.40) | ARMEN1MAPTKMT2ATRPA1 | |
| SCHEMBL2093225 | 0.71 | NOTUM (0.42) | NOTUMMEN1LMNAMAPTKMT2A | |
| SCHEMBL28549073 | 0.70 | KIF11 (0.58) | MAPTBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119019428-A | Sulfinimides class compound and application thereof | 中国药科大学 | 2024-11-26 | — | — | CN | disclosed |