SCHEMBL28344455

SCHEMBL28344455

CC(C)C(N)C(=O)N(O)c1ncnc2c1ncn2[C@]1(C(N)=O)O[C@H](CO)[C@@H](O)[C@H]1O

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ ADORA2A P29274 1/20 0.36
▸ ADORA2B P29275 1/20 0.36
▸ NPEPPS P55786 8/20 0.36
▸ ANPEP P15144 8/20 0.35
▸ SMN1; SMN2 Q16637 3/20 0.34
▸ TP53 P04637 2/20 0.34
▸ CYP3A4 P08684 2/20 0.34
▸ LMNA P02545 1/20 0.34
▸ HIF1A Q16665 1/20 0.34
▸ HTT P42858 1/20 0.34
▸ NPC1 O15118 1/20 0.34
▸ RAB9A P51151 1/20 0.34
▸ PAX8 Q06710 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31406536 1.00 ADORA2A (0.36) ADORA2AADORA2BNPEPPSANPEPSMN1; SMN2
SCHEMBL26981136 0.87 ADORA2A (0.38) ADORA2AADORA2BNPEPPSANPEPSMN1; SMN2
SCHEMBL29835052 0.87 ADORA2A (0.38) ADORA2AADORA2BNPEPPSANPEPSMN1; SMN2
SCHEMBL28521252 0.86 HTR2C (0.31) —
SCHEMBL31192291 0.86 HTR2C (0.31) —
SCHEMBL31228871 0.84 NPEPPS (0.35) ADORA2AADORA2BNPEPPSANPEPSMN1; SMN2
SCHEMBL28758954 0.83 SLC29A1 (0.37) ADORA2AADORA2BNPEPPSANPEP
SCHEMBL30042226 0.78 PI4KA (0.39) ADORA2AADORA2BSMN1; SMN2TP53LMNA
SCHEMBL2463541 0.78 ADORA3 (0.50) ADORA2AADORA2BSMN1; SMN2
SCHEMBL16987222 0.78 TARS1 (0.38) TP53LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120153078-A RNA molecules encoding RSV-F and vaccines containing the same 辉瑞大药厂 2025-06-13 — — CN disclosed
CN-120129688-A Efficient method for preparing highly purified 5' -capped oligonucleotides 垂林克生物技术有限公司 2025-06-10 — — CN disclosed
CN-119563026-A MRNA of novel coronavirus S protein and application thereof 深圳深信生物科技有限公司 2025-03-04 — — CN disclosed
CN-119562826-A Stable pre-fusion HMPV fusion proteins MSD国际商务股份有限公司 2025-03-04 — — CN disclosed
CN-119522284-A Lipid Nanoparticle (LNP) based ocular delivery 克里斯珀医疗股份公司 2025-02-25 — — CN disclosed
CN-113423418-B Treatment of cilia disease 埃泽瑞斯公司 2025-01-10 — — CN disclosed
CN-119095964-A Multi-tail and multi-cap mRNA and uses thereof 博德研究所 2024-12-06 — — CN disclosed
CN-119053705-A Methods and compositions for treating lipoprotein-related diseases 克里斯珀医疗股份公司 2024-11-29 — — CN disclosed
CN-119032176-A Methods and compositions for treating angiopoietin-like 3 (ANGPTL 3) related conditions 克里斯珀医疗股份公司 2024-11-26 — — CN disclosed
CN-118949075-A Treatment of cilia disease 埃泽瑞斯公司 2024-11-15 — — CN disclosed
CN-116133652-A Method for preparing lipid nanoparticles 摩登纳特斯有限公司 2023-05-16 — — CN disclosed
CN-109312338-B CRISPR/CAS related methods and compositions for treating herpes simplex virus 爱迪塔斯医药公司 2022-09-27 — — CN disclosed
CN-114746398-A Headgroup lipid compounds and compositions for intracellular delivery of therapeutic agents 摩登纳特斯有限公司 2022-07-12 — — CN disclosed
CN-114728887-A Branched tail end lipid compounds and compositions for intracellular delivery of therapeutic agents 摩登纳特斯有限公司 2022-07-08 — — CN disclosed
CN-114729392-A Systems and methods for barcoding cells and cell beads 10X基因组学有限公司 2022-07-08 — — CN disclosed
CN-114728886-A Carbonate-containing lipid compounds and compositions for intracellular delivery of therapeutic agents 摩登纳特斯有限公司 2022-07-08 — — CN disclosed
CN-113874503-A Systems and methods for modulating CRISPR activity 辛瑟高公司 2021-12-31 — — CN disclosed
CN-113677793-A Stable CRISPR complexes 辛瑟高公司 2021-11-19 — — CN disclosed
CN-113423418-A Treatment of cilia disease 埃泽瑞斯公司 2021-09-21 — — CN disclosed
CN-110546262-A compositions and methods for treating hemoglobinopathies NOVARTIS AG 2019-12-06 — — CN disclosed
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