Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | PDE5A | O76074 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28346130 | 0.88 | KDM4E (0.46) | KDM4EGAAKMT2AALDH1A1LMNA | |
| SCHEMBL28881130 | 0.83 | KDM4E (0.57) | KDM4EGAAKMT2AALDH1A1LMNA | |
| SCHEMBL28205313 | 0.75 | MEN1 (0.64) | KMT2AALDH1A1LMNAMEN1MAOA | |
| SCHEMBL28346117 | 0.73 | KDM4E (0.53) | KDM4EGAAKMT2AKIF11MEN1 | |
| SCHEMBL14327977 | 0.72 | L3MBTL1 (0.64) | KDM4EGAAKMT2AALDH1A1LMNA | |
| SCHEMBL28343226 | 0.68 | MAOB (0.64) | KMT2ALMNAMEN1MAOAMAOB | |
| SCHEMBL28343220 | 0.67 | MAOB (0.59) | KDM4EKMT2AALDH1A1MEN1MAOA | |
| SCHEMBL10506317 | 0.67 | SMN1; SMN2 (0.60) | KDM4EKMT2AALDH1A1LMNAHTT | |
| SCHEMBL28481286 | 0.67 | RIPK1 (0.54) | KDM4EGAAKMT2AALDH1A1LMNA | |
| SCHEMBL15517575 | 0.66 | ALDH1A1 (0.57) | KDM4EKMT2AALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107827820-B | Pyrazoline aminopeptidase N inhibitor and preparation method and application thereof | 山东大学 | 2020-01-07 | — | — | CN | claimed |
| CN-107827820-B | Pyrazoline aminopeptidase N inhibitor and preparation method and application thereof | 山东大学 | 2020-01-07 | — | — | CN | disclosed |