SCHEMBL28346293

SCHEMBL28346293

Brc1ccccc1CSc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.46
MAPK1 P28482 1/20 0.46
TAAR1 Q96RJ0 3/20 0.43
KMT2A Q03164 3/20 0.43
CDC7 O00311 1/20 0.43
DBF4 Q9UBU7 1/20 0.43
PTGDR2 Q9Y5Y4 1/20 0.42
IDO1 P14902 2/20 0.42
MEN1 O00255 2/20 0.41
MGAM O43451 1/20 0.41
GAA P10253 1/20 0.41
SI P14410 1/20 0.41
MGAM2 Q2M2H8 1/20 0.41
PPARG P37231 1/20 0.40
LMNA P02545 2/20 0.40
RAB9A P51151 2/20 0.40
PTK2 Q05397 1/20 0.40
NPC1 O15118 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
TERT O14746 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28497830 0.84 GAA (0.54) ALDH1A1MAPK1TAAR1KMT2ACDC7
SCHEMBL28096427 0.80 TERT (0.48) ALDH1A1MAPK1KMT2ACDC7DBF4
SCHEMBL22116739 0.79 ANPEP (0.46) TAAR1KMT2ACDC7DBF4PTGDR2
SCHEMBL10662839 0.78 ALDH1A1 (0.41) ALDH1A1MAPK1KMT2AMEN1LMNA
SCHEMBL14328044 0.77 ALDH1A1 (0.43) ALDH1A1MAPK1KMT2AIDO1MEN1
SCHEMBL28179237 0.77 TAAR1 (0.50) TAAR1KMT2ACDC7DBF4IDO1
SCHEMBL5855074 0.77 TAAR1 (0.50) ALDH1A1TAAR1CDC7DBF4IDO1
Cyanide SCHEMBL28319714 0.76 PIEZO1 (0.40) ALDH1A1MAPK1KMT2AMEN1MGAM
SCHEMBL8022137 0.75 POLB (0.57) MAPK1TAAR1KMT2ACDC7DBF4
SCHEMBL28388549 0.75 GAA (0.40) ALDH1A1TAAR1KMT2ACDC7DBF4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110655538-B Mono-metallocene trivalent transition metal complex containing neutral benzyl heteroatom ligand and application thereof JILIN UNIVERSITY (CN) 2021-08-31 CN disclosed
CN-110655538-A Mono-metallocene trivalent transition metal complex containing neutral benzyl heteroatom ligand and application thereof 吉林大学 2020-01-07 CN disclosed