Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GSTP1 | P09211 | 3/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17026736 | 0.82 | ACACB (0.53) | MAPTALDH1A1HTTTDP1ACACB | |
| SCHEMBL17039174 | 0.78 | ACACB (0.50) | MAPTALDH1A1HTTTDP1ACACB | |
| SCHEMBL29758972 | 0.75 | MAPT (0.66) | MAPTHTTTDP1LMNARAB9A | |
| SCHEMBL190096 | 0.73 | FFAR1 (0.60) | MAPTTDP1RAB9ATSHRFFAR1 | |
| SCHEMBL28346942 | 0.72 | MMP2 (0.58) | MAPTALDH1A1HTTACACBLMNA | |
| SCHEMBL28343633 | 0.71 | MMP2 (0.77) | MMP2MMP9MMP14 | |
| SCHEMBL8892261 | 0.66 | LMNA (0.64) | MAPTALDH1A1HTTTDP1LMNA | |
| SCHEMBL17039180 | 0.66 | LMNA (0.48) | MAPTALDH1A1LMNARAB9AKMT2A | |
| SCHEMBL10187438 | 0.66 | ALDH1A1 (0.50) | MAPTALDH1A1TDP1RAB9ATSHR | |
| SCHEMBL314128 | 0.64 | ALDH1A1 (0.46) | MAPTALDH1A1HTTRAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106536500-B | Selective matrix metalloproteinase inhibitors | 圣母大学 | 2020-01-10 | — | — | CN | disclosed |