Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7213005 | 0.89 | LMNA (0.52) | RAB9AKMT2AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL5893770 | 0.87 | CA12 (0.51) | RAB9AKMT2AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL20544339 | 0.84 | HSP90AA1 (0.52) | RAB9AKMT2AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL20544340 | 0.84 | HSP90AA1 (0.52) | RAB9AKMT2AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL28602892 | 0.83 | KMT2A (0.46) | RAB9AKMT2AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL9724555 | 0.82 | POLB (0.61) | KMT2AALDH1A1SMN1; SMN2MEN1MAPT | |
| SCHEMBL6852892 | 0.78 | L3MBTL1 (0.38) | RAB9AKMT2AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL3329607 | 0.78 | L3MBTL1 (0.38) | RAB9AKMT2AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL3592465 | 0.76 | RAB9A (1.00) | RAB9AKMT2AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL3592470 | 0.76 | RAB9A (1.00) | RAB9AKMT2AALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108640887-B | Heterocyclic morpholine derivatives, and preparation method and application thereof | 南开大学 | 2019-12-24 | — | — | CN | disclosed |