SCHEMBL7213005

SCHEMBL7213005

O=C(/C=C/c1ccccc1)ON1CC1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.52
MAPT P10636 3/20 0.52
HDAC3 O15379 2/20 0.52
HDAC4 P56524 2/20 0.52
HDAC1 Q13547 2/20 0.52
HDAC2 Q92769 2/20 0.52
HDAC8 Q9BY41 2/20 0.52
HDAC6 Q9UBN7 2/20 0.52
PLIN1 O60240 2/20 0.52
RECQL P46063 2/20 0.52
PLIN5 Q00G26 2/20 0.52
ABHD5 Q8WTS1 2/20 0.52
ALDH1A1 P00352 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
TNKS O95271 1/20 0.52
HCAR2 Q8TDS4 1/20 0.52
HDAC7 Q8WUI4 1/20 0.52
HDAC10 Q969S8 1/20 0.52
HDAC11 Q96DB2 1/20 0.52
TNKS2 Q9H2K2 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9724555 0.92 POLB (0.61) LMNAMAPTHDAC3HDAC4HDAC1
SCHEMBL20544339 0.92 HSP90AA1 (0.52) LMNAMAPTHDAC3HDAC4HDAC1
SCHEMBL20544340 0.92 HSP90AA1 (0.52) LMNAMAPTHDAC3HDAC4HDAC1
SCHEMBL28602892 0.90 KMT2A (0.46) LMNAMAPTHDAC3HDAC4HDAC1
SCHEMBL28347103 0.89 RAB9A (0.61) LMNAMAPTHDAC3HDAC4HDAC1
SCHEMBL1711201 0.78 LMNA (0.47) LMNAMAPTHDAC3HDAC4HDAC1
SCHEMBL7882197 0.78 LMNA (0.47) LMNAMAPTHDAC3HDAC4HDAC1
SCHEMBL10860851 0.77 ALDH1A1 (0.57) LMNAMAPTALDH1A1CYP2C9KMT2A
SCHEMBL28352997 0.77 KMT2A (0.43) LMNAMAPTHDAC3HDAC4HDAC1
SCHEMBL21803794 0.77 MAPT (0.64) LMNAMAPTHDAC3HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6582784-B2 Thermostability and photosensitivity LG.PHILIPS LCD CO., LTD. (KR) 2003-06-24 US disclosed
US-6383579-B1 POLYETHYLENIMINIE CINNAMATE ALIGNMENT LAYER WITH PHOTOSENSITIVE CONSTITUENT; HEAT RESISTANCE LG. PHILIPS LCD CO., LTD. (KR) 2002-05-07 US disclosed