Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 3/20 | 0.72 |
| ▸ | FLT4 | P35916 | 3/20 | 0.72 |
| ▸ | KDR | P35968 | 3/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | MMP1 | P03956 | 1/20 | 0.55 |
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.55 |
| ▸ | MMP8 | P22894 | 1/20 | 0.55 |
| ▸ | MMP13 | P45452 | 1/20 | 0.55 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14607436 | 0.87 | ALDH1A1 (0.59) | FLT1FLT4KDRKMT2APOLB | |
| SCHEMBL15449709 | 0.86 | ALDH1A1 (0.76) | FLT1FLT4KDRKMT2APOLB | |
| SCHEMBL4485832 | 0.84 | FLT1 (0.65) | FLT1FLT4KDRKMT2ATP53 | |
| SCHEMBL9659192 | 0.84 | FLT1 (0.78) | FLT1FLT4KDRKMT2ATP53 | |
| SCHEMBL31060566 | 0.84 | FLT1 (1.00) | FLT1FLT4KDR | |
| SCHEMBL11442730 | 0.84 | FLT1 (0.82) | FLT1FLT4KDRPOLBMAPT | |
| SCHEMBL10223118 | 0.83 | NPC1 (0.56) | FLT1FLT4KDRKMT2ATP53 | |
| SCHEMBL4472735 | 0.82 | ALDH1A1 (0.53) | FLT1FLT4KDRKMT2APOLB | |
| SCHEMBL9967797 | 0.81 | CA1 (0.64) | FLT1FLT4KDRKMT2APOLB | |
| SCHEMBL3306626 | 0.80 | FLT1 (0.76) | FLT1FLT4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7605111-B2 | Herbicides | SYNGENTA CROP PROTECTION, INC. (US) | 2009-10-20 | — | — | US | disclosed |
| US-7459414-B2 | Herbicides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-12-02 | — | — | US | disclosed |
| US-20080200336-A1 | HERBICIDAL COMPOSITION | SYNEGENTA CROP PROTECTION, INC. (US) | 2008-08-21 | — | — | US | disclosed |
| EP-1481970-B1 | Novel herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2006-03-22 | — | — | EP | disclosed |
| US-6962894-B1 | comprise a herbicide and a safener (counter-agent, antidote) and protect the useful plants, but not the weeds, against the phytotoxic action of the herbicide | SYNGENTA CROP PROTECTION, INC. (US) | 2005-11-08 | — | — | US | disclosed |
| US-20050187110-A1 | mixtures with plant safening agents used for selectively controlling weeds and grasses in crops of useful plants | MAETZKE THOMAS (CH) | 2005-08-25 | — | — | US | disclosed |
| US-20050164886-A1 | Herbicidal compositions | ALSONS CORPORATION | 2005-07-28 | — | — | US | disclosed |
| US-20050164883-A1 | agronomically tolerable salts, isomers and enantiomers of those compounds, are suitable for use as herbicides | MAETZKE THOMAS (CH) | 2005-07-28 | — | — | US | disclosed |
| US-6894005-B1 | Heterocyclic compound containing phenyl groups; postemergence herbicides | SYNGENTA CROP PROTECTION, INC. (US) | 2005-05-17 | — | — | US | disclosed |
| US-20050090399-A1 | Phenyl substituted heterocyclic compounds useful as herbicides | FRIEDMANN ADRIAN A (GB) | 2005-04-28 | — | — | US | disclosed |
| EP-1481970-A1 | Novel herbicides | Syngenta Participations AG (CH) | 2004-12-01 | — | — | EP | disclosed |
| EP-1210333-B1 | p-Tolyl-heterocycles as herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2004-11-17 | — | — | EP | disclosed |
| EP-1468000-A1 | PHENYL SUBSTITUTED HETEROCYCLIC COMPOUNDS USEFUL AS HERBICIDES | Syngenta Participations AG (CH) | 2004-10-20 | — | — | EP | disclosed |
| WO-2003062244-A1 | PHENYL SUBSTITUTED HETEROCYCLIC COMPOUNDS USEFUL AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2003-07-31 | — | — | WO | disclosed |
| EP-1210333-A2 | NOVEL HERBICIDES | Syngenta Participations AG (CH) | 2002-06-05 | — | — | EP | disclosed |
| EP-1209975-A1 | HERBICIDAL COMPOSITION | Syngenta Participations AG (CH) | 2002-06-05 | — | — | EP | disclosed |
| WO-2001017353-A1 | HERBICIDAL COMPOSITION | SYNGENTA PARTICIPATIONS AG (CH) | 2001-03-15 | — | — | WO | disclosed |
| WO-2001017972-A2 | NOVEL HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-03-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050164886-A1 | Herbicidal compositions | CBR3, CBR1, CNPY2 | FLT1 4773/4885FLT4 4358/4885KDR 3983/4885 |
| US-20050164883-A1 | agronomically tolerable salts, isomers and enantiomers of those compounds, are suitable for use as herbicides | DDT, SULT2A1, GSTA1 | FLT1 2672/4885FLT4 3556/4885KDR 2780/4885 |
| US-20080200336-A1 | HERBICIDAL COMPOSITION | MTX2, DDT, AGPS | FLT1 3754/4885FLT4 4080/4885KDR 3400/4885 |
| US-20050090399-A1 | Phenyl substituted heterocyclic compounds useful as herbicides | DDT, PAH, CYP1A1 | FLT1 1455/4885FLT4 2559/4885KDR 2796/4885 |
| US-20050187110-A1 | mixtures with plant safening agents used for selectively controlling weeds and grasses in crops of useful plants | PIN1, GMDS, DDT | FLT1 3866/4885FLT4 4279/4885KDR 4212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.