Sugi Predict

Sugi Predict / Compounds / SCHEMBL2834740

SCHEMBL2834740

SCHEMBL2834740

c1cc(N2CCC3(CCNC3)C2)ccn1

nearest known ligand 0.70

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ CYP3A4 P08684 10/20 0.68
▸ ALDH1A1 P00352 7/20 0.68
▸ CYP2D6 P10635 7/20 0.68
▸ CYP2C19 P33261 7/20 0.68
▸ CYP2C9 P11712 5/20 0.68
▸ TSHR P16473 4/20 0.68
▸ USP2 O75604 5/20 0.60
▸ CYP1A2 P05177 4/20 0.60
▸ HSD17B10 Q99714 5/20 0.55
▸ MAPK1 P28482 3/20 0.55
▸ HPGD P15428 2/20 0.55
▸ TP53 P04637 2/20 0.55
▸ SMN1; SMN2 Q16637 1/20 0.55
▸ ADRB2 P07550 1/20 0.50
▸ NCF1 P14598 1/20 0.50
▸ PLD1 Q13393 1/20 0.50
▸ HIF1A Q16665 1/20 0.48
▸ MEN1 O00255 1/20 0.47
▸ KMT2A Q03164 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL485785 0.98 CYP3A4 (0.67) CYP3A4ALDH1A1CYP2D6CYP2C19CYP2C9
SCHEMBL13131243 0.91 CYP3A4 (0.83) CYP3A4ALDH1A1CYP2D6CYP2C19CYP2C9
SCHEMBL3087549 0.91 CYP3A4 (0.74) CYP3A4ALDH1A1CYP2D6CYP2C19CYP2C9
SCHEMBL3082414 0.90 CYP2D6 (0.59) CYP3A4ALDH1A1CYP2D6CYP2C19CYP2C9
SCHEMBL939303 0.90 CYP3A4 (0.82) CYP3A4ALDH1A1CYP2D6CYP2C19CYP2C9
Hydrochloric Acid SCHEMBL2816934 0.90 CYP3A4 (0.81) CYP3A4ALDH1A1CYP2D6CYP2C19CYP2C9
Hydrochloric Acid SCHEMBL2817996 0.90 CYP3A4 (0.72) CYP3A4ALDH1A1CYP2D6CYP2C19CYP2C9
Hydrochloric Acid SCHEMBL18789104 0.89 CYP2D6 (0.57) CYP3A4ALDH1A1CYP2D6CYP2C19CYP2C9
Hydrochloric Acid SCHEMBL484648 0.89 CYP3A4 (0.80) CYP3A4ALDH1A1CYP2D6CYP2C19CYP2C9
Hydrochloric Acid SCHEMBL7008715 0.89 CYP3A4 (0.80) CYP3A4ALDH1A1CYP2D6CYP2C19CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119775261-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2025-04-08 — — CN disclosed
CN-115427404-B Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2024-12-13 — — CN disclosed
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-05-18 — — US disclosed
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-05-18 — — US disclosed
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-05-18 — — US disclosed
EP-4139291-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF Anima Biotech Inc. (US) 2023-03-01 — — EP disclosed
CN-115427404-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2022-12-02 — — CN disclosed
WO-2021216665-A9 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-12-02 — — WO disclosed
WO-2021216665-A9 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-12-02 — — WO disclosed
WO-2021216665-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-10-28 — — WO disclosed
US-20100234340-A1 Substituted Spiroamide Compounds GRUENENTHAL GMBH (DE) 2010-09-16 — — US disclosed
US-20100234340-A1 Substituted Spiroamide Compounds GRUENENTHAL GMBH (DE) 2010-09-16 — — US disclosed
US-20100222324-A1 Substituted Indole Compounds GRUENENTHAL GMBH (DE) 2010-09-02 — — US disclosed
US-20100222324-A1 Substituted Indole Compounds GRUENENTHAL GMBH (DE) 2010-09-02 — — US disclosed
US-20100173889-A1 Substituted Pyrimidine and Triazine Compounds GRUENENTHAL GMBH (DE) 2010-07-08 — — US disclosed
US-20100173889-A1 Substituted Pyrimidine and Triazine Compounds GRUENENTHAL GMBH (DE) 2010-07-08 — — US disclosed
US-20100173889-A1 Substituted Pyrimidine and Triazine Compounds GRUENENTHAL GMBH (DE) 2010-07-08 — — US disclosed
US-20100152158-A1 Substituted Disulfonamide Compounds GRUENENTHAL GMBH (DE) 2010-06-17 — — US disclosed
US-20100152158-A1 Substituted Disulfonamide Compounds GRUENENTHAL GMBH (DE) 2010-06-17 — — US disclosed
WO-2010051977-A1 SUBSTITUTED DISULFONAMIDES AS BRI-MODULATORS Grünenthal GmbH (DE) 2010-05-14 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF COL1A1, COL2A1, COL14A1 CYP3A4 4190/4885ALDH1A1 1196/4885CYP2D6 4382/4885
US-20100152158-A1 Substituted Disulfonamide Compounds BDKRB1, BDKRB2, BRS3 CYP3A4 2223/4885ALDH1A1 1278/4885CYP2D6 1247/4885
US-20100222324-A1 Substituted Indole Compounds BDKRB1, BDKRB2, EDNRB CYP3A4 1993/4885ALDH1A1 1551/4885CYP2D6 585/4885
US-20100173889-A1 Substituted Pyrimidine and Triazine Compounds ADORA2B, CCNB1, TYMS CYP3A4 1682/4885ALDH1A1 2375/4885CYP2D6 1157/4885
US-20100234340-A1 Substituted Spiroamide Compounds BDKRB1, BDKRB2, AVPR1B CYP3A4 1215/4885ALDH1A1 1303/4885CYP2D6 950/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.