SCHEMBL2834883

SCHEMBL2834883

CC(=O)C=Cc1ccccc1C

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.66
LMNA P02545 3/20 0.66
KDM4E B2RXH2 3/20 0.59
IAPP P10997 1/20 0.56
GLA P06280 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
ALDH1A1 P00352 3/20 0.50
TSHR P16473 2/20 0.50
RAB9A P51151 2/20 0.48
KMT2A Q03164 2/20 0.45
ATM Q13315 1/20 0.45
MEN1 O00255 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
GMNN O75496 1/20 0.44
PMP22 Q01453 1/20 0.44
NFE2L2 Q16236 2/20 0.44
NFKB1 P19838 2/20 0.44
JUN P05412 1/20 0.44
CYP1A2 P05177 2/20 0.43
CYP2C19 P33261 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7899013 1.00 MAPT (0.66) MAPTLMNAKDM4EIAPPGLA
SCHEMBL14279409 1.00 MAPT (0.66) MAPTLMNAKDM4EIAPPGLA
SCHEMBL31422587 1.00 MAPT (0.66) MAPTLMNAKDM4EIAPPGLA
SCHEMBL14441077 0.87 MAPT (0.76) MAPTLMNAKDM4EIAPPGLA
SCHEMBL15853343 0.86 LMNA (0.50) MAPTLMNAKDM4EIAPPGLA
SCHEMBL5598952 0.85 NFE2L2 (0.61) MAPTLMNAKDM4ETDP1ALDH1A1
SCHEMBL5598954 0.85 NFE2L2 (0.61) MAPTLMNAKDM4ETDP1ALDH1A1
SCHEMBL78556 0.83 CA1 (0.62) MAPTLMNAKDM4EALDH1A1TSHR
SCHEMBL78555 0.83 CA1 (0.62) MAPTLMNAKDM4EALDH1A1TSHR
SCHEMBL2425317 0.83 CA1 (0.62) MAPTLMNAKDM4EALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112430473-B Method for synthesizing biomass high-density aviation fuel by using damascenone as raw material 西安交通大学 2021-08-13 CN claimed
CN-112430473-A Method for synthesizing biomass high-density aviation fuel by using damascenone as raw material 西安交通大学 2021-03-02 CN claimed
CN-102300550-A Perfume systems 2011-12-28 CN claimed
CN-115232019-B Synthesis method of 3-acetamido benzotrifluoride compound 闽江学院 2023-10-27 CN disclosed
CN-115232019-A Synthetic method of 3-acetamido benzotrifluoride compound 闽江学院 2022-10-25 CN disclosed
CN-112430473-B Method for synthesizing biomass high-density aviation fuel by using damascenone as raw material 西安交通大学 2021-08-13 CN disclosed
CN-112430473-A Method for synthesizing biomass high-density aviation fuel by using damascenone as raw material 西安交通大学 2021-03-02 CN disclosed
CN-106631742-A A method of preparing alpha,beta-unsaturated ketones 江南大学 2017-05-10 CN disclosed
CN-101980865-A Hydrophilic member, fin member, aluminum fin member, heat exchanger and air conditioner FUJIFILM CORP 2011-02-23 CN disclosed
CN-1737682-B Planographic printing plate precursor FUJI PHOTO FILM CO LTD 2011-01-19 CN disclosed
CN-101932447-A Hydrophilic element FUJIFILM CORP 2010-12-29 CN disclosed
US-6177462-B1 Unsaturated oxime ethers and their use as fungicides and insecticides ROHM AND HAAS COMPANY 2001-01-23 US disclosed
EP-0936213-A1 Unsaturated oxime ethers and their use as fungicides and insecticides ROHM AND HAAS COMPANY (US) 1999-08-18 EP disclosed
US-5484949-A Method for the synthesis of α β-unsaturated ketones NIPPON SODA CO., LTD. (JP) 1996-01-16 US disclosed
EP-0195053-B1 PROCESS FOR PREPARING 1,3-CYCLOHEXANEDIONE DERIVATIVES AND INTERMEDIATES THEREFOR CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1992-02-12 EP disclosed
EP-0454867-A1 A METHOD FOR THE SYNTHESIS OF -g(a), -g(b)-UNSATURATED KETONES. NIPPON SODA CO (JP) 1991-11-06 EP disclosed
WO-1991007370-A1 A METHOD FOR THE SYNTHESIS OF α, β-UNSATURATED KETONES NIPPON SODA CO., LTD. (JP) 1991-05-30 WO disclosed
EP-0195053-A1 PROCESS FOR PREPARING 1,3-CYCLOHEXANEDIONE DERIVATIVES AND INTERMEDIATES THEREFOR. CHEVRON RES & TECH (US) 1986-09-24 EP disclosed
WO-1986002065-A1 PROCESS FOR PREPARING 1,3-CYCLOHEXANEDIONE DERIVATIVES AND INTERMEDIATES THEREFOR CHEVRON RESEARCH COMPANY (US) 1986-04-10 WO disclosed
US-3989708-A HYPOTENSIVE, CORONARY VESSEL DILATORS BAYER AKTIENGESELLSCHAFT (DT) 1976-11-02 US disclosed