Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | IAPP | P10997 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | JUN | P05412 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14279409 | 1.00 | MAPT (0.66) | MAPTLMNAKDM4EIAPPGLA | |
| SCHEMBL2834883 | 1.00 | MAPT (0.66) | MAPTLMNAKDM4EIAPPGLA | |
| SCHEMBL31422587 | 1.00 | MAPT (0.66) | MAPTLMNAKDM4EIAPPGLA | |
| SCHEMBL14441077 | 0.87 | MAPT (0.76) | MAPTLMNAKDM4EIAPPGLA | |
| SCHEMBL15853343 | 0.86 | LMNA (0.50) | MAPTLMNAKDM4EIAPPGLA | |
| SCHEMBL5598952 | 0.85 | NFE2L2 (0.61) | MAPTLMNAKDM4ETDP1ALDH1A1 | |
| SCHEMBL5598954 | 0.85 | NFE2L2 (0.61) | MAPTLMNAKDM4ETDP1ALDH1A1 | |
| SCHEMBL78556 | 0.83 | CA1 (0.62) | MAPTLMNAKDM4EALDH1A1TSHR | |
| SCHEMBL78555 | 0.83 | CA1 (0.62) | MAPTLMNAKDM4EALDH1A1TSHR | |
| SCHEMBL2425317 | 0.83 | CA1 (0.62) | MAPTLMNAKDM4EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110713436-B | Method for carrying out 1, 4-conjugated reduction by photochemical catalysis of alpha, beta-ketene compound | 北京工商大学 | 2022-06-14 | — | — | CN | claimed |
| EP-4727923-A1 | TETRAHYDROACRIDINONE ANALOGUES FOR TREATMENT AND PREVENTION OF MALARIA | University of Georgia Research Foundation, Inc. (US) | 2026-04-22 | — | — | EP | disclosed |
| US-20260098012-A1 | TETRAHYDROACRIDINONE ANALOGUES FOR TREATMENT AND PREVENTION OF MALARIA | UNIV GEORGIA (US) | 2026-04-09 | — | — | US | disclosed |
| WO-2024258904-A1 | TETRAHYDROACRIDINONE ANALOGUES FOR TREATMENT AND PREVENTION OF MALARIA | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2024-12-19 | — | — | WO | disclosed |
| US-11807619-B2 | Para acyl substituted diazacyclohexene derivatives | Renovel Innovations, Inc. | 2023-11-07 | — | — | US | disclosed |
| US-11807619-B2 | Para acyl substituted diazacyclohexene derivatives | Renovel Innovations, Inc. | 2023-11-07 | — | — | US | disclosed |
| CN-110713436-B | Method for carrying out 1, 4-conjugated reduction by photochemical catalysis of alpha, beta-ketene compound | 北京工商大学 | 2022-06-14 | — | — | CN | disclosed |
| CN-112266352-B | Piperlongumine derivative and preparation method and application thereof | 绍兴文理学院 | 2022-02-08 | — | — | CN | disclosed |
| CN-112266352-A | Piperlongumine derivative and preparation method and application thereof | 绍兴文理学院 | 2021-01-26 | — | — | CN | disclosed |
| CN-110713436-A | Method for carrying out 1, 4-conjugated reduction by photochemical catalysis of alpha, beta-ketene compound | 北京工商大学 | 2020-01-21 | — | — | CN | disclosed |
| US-9102665-B2 | Cysteinyl leukotriene antagonists | SUN PHARMA ADVANCED RESEARCH COMPANY LTD. (IN) | 2015-08-11 | — | — | US | disclosed |
| US-20140155596-A1 | CYSTEINYL LEUKOTRIENE ANTAGONISTS | SUN PHARMA ADVANCED RESEARCH COMPANY LTD. (IN) | 2014-06-05 | — | — | US | disclosed |
| US-6177462-B1 | Unsaturated oxime ethers and their use as fungicides and insecticides | ROHM AND HAAS COMPANY | 2001-01-23 | — | — | US | disclosed |
| EP-0936213-A1 | Unsaturated oxime ethers and their use as fungicides and insecticides | ROHM AND HAAS COMPANY (US) | 1999-08-18 | — | — | EP | disclosed |
| US-5484949-A | Method for the synthesis of α β-unsaturated ketones | NIPPON SODA CO., LTD. (JP) | 1996-01-16 | — | — | US | disclosed |
| EP-0195053-B1 | PROCESS FOR PREPARING 1,3-CYCLOHEXANEDIONE DERIVATIVES AND INTERMEDIATES THEREFOR | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1992-02-12 | — | — | EP | disclosed |
| EP-0454867-A1 | A METHOD FOR THE SYNTHESIS OF -g(a), -g(b)-UNSATURATED KETONES. | NIPPON SODA CO (JP) | 1991-11-06 | — | — | EP | disclosed |
| WO-1991007370-A1 | A METHOD FOR THE SYNTHESIS OF α, β-UNSATURATED KETONES | NIPPON SODA CO., LTD. (JP) | 1991-05-30 | — | — | WO | disclosed |
| EP-0195053-A1 | PROCESS FOR PREPARING 1,3-CYCLOHEXANEDIONE DERIVATIVES AND INTERMEDIATES THEREFOR. | CHEVRON RES & TECH (US) | 1986-09-24 | — | — | EP | disclosed |
| WO-1986002065-A1 | PROCESS FOR PREPARING 1,3-CYCLOHEXANEDIONE DERIVATIVES AND INTERMEDIATES THEREFOR | CHEVRON RESEARCH COMPANY (US) | 1986-04-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11807619-B2 | Para acyl substituted diazacyclohexene derivatives | AADAC, TBXA2R, DPP8 | MAPT 4652/4885LMNA 1601/4885KDM4E 2000/4885 |
| US-20260098012-A1 | TETRAHYDROACRIDINONE ANALOGUES FOR TREATMENT AND PREVENTION OF MALARIA | CD47, SLC11A2, G6PD | MAPT 2146/4885LMNA 297/4885KDM4E 1264/4885 |
| US-20140155596-A1 | CYSTEINYL LEUKOTRIENE ANTAGONISTS | LTC4S, CYSLTR2, CYSLTR1 | MAPT 4832/4885LMNA 1681/4885KDM4E 2559/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.