SCHEMBL2835005

SCHEMBL2835005

CC(C)=CCOC(=O)c1cccc(F)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.50
ADRB1 P08588 1/20 0.50
ADRB3 P13945 1/20 0.50
MMP1 P03956 1/20 0.50
MMP2 P08253 1/20 0.50
MMP9 P14780 1/20 0.50
MMP12 P39900 1/20 0.50
CES2 O00748 1/20 0.47
CES1 P23141 1/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
ALDH1A1 P00352 2/20 0.46
KMT2A Q03164 2/20 0.46
ESR1 P03372 1/20 0.46
ESR2 Q92731 1/20 0.46
PARP1 P09874 1/20 0.45
TRPV1 Q8NER1 1/20 0.45
PKM P14618 1/20 0.44
MEN1 O00255 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27759174 0.83 MMP1 (0.51) MMP1MMP2MMP9MMP12RAB9A
SCHEMBL2834425 0.82 ADRB2 (0.50) ADRB2ADRB1ADRB3CES2CES1
SCHEMBL2834424 0.82 ADRB2 (0.50) ADRB2ADRB1ADRB3CES2CES1
SCHEMBL2831834 0.81 CYP3A4 (0.53) ADRB2ADRB1ADRB3CES2CES1
SCHEMBL2833266 0.81 TRPV1 (0.56) ADRB2ADRB1ADRB3MMP1MMP2
Benzoic Acid 3-Methyl-2-Butenyl Ester SCHEMBL873002 0.80 TRPV1 (0.55) MMP1MMP2MMP9MMP12NPC1
SCHEMBL2834462 0.80 MMP1 (0.54) MMP1MMP2MMP9MMP12CES2
SCHEMBL641903 0.79 POLB (0.62) ADRB2ADRB1ADRB3CES2CES1
SCHEMBL31237097 0.79 POLB (0.62) ADRB2ADRB1ADRB3CES2CES1
SCHEMBL29934134 0.77 CES2 (0.57) ADRB2ADRB1ADRB3CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101595082-B Ester compound, and non-aqueous electrolyte solution and lithium secondary battery each using the ester compound UBE INDUSTRIES 2013-08-21 CN disclosed
US-8263268-B2 Ester compound, and non-aqueous electrolyte solution and lithium secondary battery each using the ester compound UBE INDUSTRIES, LTD. (JP) 2012-09-11 US disclosed
EP-2108640-B1 ESTER COMPOUND, AND NON-AQUEOUS ELECTROLYTE SOLUTION AND LITHIUM SECONDARY BATTERY EACH USING THE ESTER COMPOUND UBE INDUSTRIES (JP) 2012-07-25 EP disclosed
US-20100119955-A1 ESTER COMPOUND, AND NON-AQUEOUS ELECTROLYTE SOLUTION AND LITHIUM SECONDARY BATTERY EACH USING THE ESTER COMPOUND UBE INDUSTRIES, LTD. (JP) 2010-05-13 US disclosed
EP-2108640-A1 ESTER COMPOUND, AND NON-AQUEOUS ELECTROLYTE SOLUTION AND LITHIUM SECONDARY BATTERY EACH USING THE ESTER COMPOUND Ube Industries, Ltd. (JP) 2009-10-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100119955-A1 ESTER COMPOUND, AND NON-AQUEOUS ELECTROLYTE SOLUTION AND LITHIUM SECONDARY BATTERY EACH USING THE ESTER COMPOUND CEL, LAGE3, PEF1 ADRB2 4525/4885ADRB1 4720/4885ADRB3 4711/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.