SCHEMBL28350464

SCHEMBL28350464

CCc1cc(C)c(CC)c(C)c1C

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGK1 P00558 1/20 0.35
PGK2 P07205 1/20 0.35
NOS3 P29474 2/20 0.34
NOS2 P35228 2/20 0.34
NOS1 P29475 1/20 0.34
ALDH1A1 P00352 4/20 0.32
MAPT P10636 1/20 0.32
HTT P42858 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
GRIN2D O15399 1/20 0.30
GRIN3B O60391 1/20 0.30
GRIN1 Q05586 1/20 0.30
GRIN2A Q12879 1/20 0.30
GRIN2B Q13224 1/20 0.30
GRIN2C Q14957 1/20 0.30
GRIN3A Q8TCU5 1/20 0.30
CYP1A2 P05177 1/20 0.30
ALOX15 P16050 1/20 0.30
CASP7 P55210 1/20 0.30
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28347480 0.85 PGK1 (0.40) PGK1PGK2NOS3NOS2NOS1
SCHEMBL25949658 0.82 PTGS1 (0.42) MAPTNPSR1CYP1A2ALOX15HSD17B10
SCHEMBL17373679 0.80 NOS3 (0.34) PGK1PGK2NOS3NOS2NOS1
SCHEMBL4085470 0.80 NOS3 (0.34) PGK1PGK2NOS3NOS2NOS1
SCHEMBL25328308 0.79 MAOA (0.38) PGK1PGK2ALDH1A1MAPTNPSR1
SCHEMBL11363943 0.79 GABRA1 (0.38) PGK1PGK2ALDH1A1MAPTHTT
SCHEMBL1087300 0.79 NOS3 (0.37) PGK1PGK2NOS3NOS2NOS1
SCHEMBL9628918 0.79 PGK1 (0.38) PGK1PGK2NOS3NOS2
SCHEMBL28166915 0.78 PGK1 (0.46) PGK1PGK2NOS3NOS2NOS1
SCHEMBL8097110 0.77 NOS3 (0.40) PGK1PGK2NOS3NOS2NOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110734396-A Organic compound, high polymer, mixture, composition and organic electronic device 广州华睿光电材料有限公司 2020-01-31 CN disclosed