Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 2/20 | 0.36 |
| ▸ | RXRB | P28702 | 2/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28350464 | 0.82 | PGK1 (0.35) | NPSR1ALOX15MAPTHSD17B10CYP1A2 | |
| SCHEMBL18685992 | 0.81 | PTGS1 (0.45) | PTGS1PTGS2NPSR1ALOX15SMN1; SMN2 | |
| SCHEMBL1259129 | 0.80 | ALOX15 (0.49) | PTGS1PTGS2NPSR1ALOX15SMN1; SMN2 | |
| SCHEMBL30990555 | 0.80 | ALOX15 (0.49) | PTGS1PTGS2NPSR1ALOX15SMN1; SMN2 | |
| Phosphine SCHEMBL28245494 | 0.79 | ALOX15 (0.47) | PTGS1PTGS2NPSR1ALOX15SMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL28842319 | 0.79 | ALOX15 (0.47) | PTGS1PTGS2NPSR1ALOX15SMN1; SMN2 | |
| SCHEMBL16527228 | 0.78 | ALOX15 (0.50) | PTGS1PTGS2NPSR1ALOX15SMN1; SMN2 | |
| SCHEMBL11325941 | 0.75 | NPSR1 (0.60) | PTGS1PTGS2NPSR1ALOX15SMN1; SMN2 | |
| SCHEMBL25949767 | 0.75 | THRB (0.44) | HPGDTSHRPOLBMAPTKDM4E | |
| SCHEMBL28347480 | 0.73 | PGK1 (0.40) | NPSR1ALOX15MAPTHSD17B10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242471-A1 | THYROMIMETICS | AUTOBAHN THERAPEUTICS, INC. | 2023-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242471-A1 | THYROMIMETICS | TPO, THOP1, THRB | PTGS1 367/4885PTGS2 1091/4885NPSR1 757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.