Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC12A2 | P55011 | 1/20 | 0.47 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19285370 | 1.00 | SLC12A2 (0.47) | SLC12A2SLC12A5CYP2D6ALDH1A1CYP3A4 | |
| SCHEMBL19285120 | 1.00 | SLC12A2 (0.47) | SLC12A2SLC12A5CYP2D6ALDH1A1CYP3A4 | |
| SCHEMBL283634 | 0.92 | SLC12A2 (0.56) | SLC12A2SLC12A5ALDH1A1MEN1KMT2A | |
| SCHEMBL283635 | 0.92 | SLC12A2 (0.56) | SLC12A2SLC12A5ALDH1A1MEN1KMT2A | |
| SCHEMBL2306082 | 0.92 | SLC12A2 (0.56) | SLC12A2SLC12A5ALDH1A1MEN1KMT2A | |
| SCHEMBL1691225 | 0.91 | SLC12A2 (0.52) | SLC12A2SLC12A5CYP2D6ALDH1A1CYP3A4 | |
| SCHEMBL1691084 | 0.91 | SLC12A2 (0.52) | SLC12A2SLC12A5CYP2D6ALDH1A1CYP3A4 | |
| SCHEMBL284269 | 0.91 | SLC12A2 (0.52) | SLC12A2SLC12A5CYP2D6ALDH1A1CYP3A4 | |
| SCHEMBL3649652 | 0.87 | CYP2D6 (0.43) | SLC12A2SLC12A5CYP2D6ALDH1A1CYP3A4 | |
| SCHEMBL3641686 | 0.87 | CYP2D6 (0.43) | SLC12A2SLC12A5CYP2D6ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12540126-B2 | Method for preparing oxetan-2-ylmethanamine | ACCELA CHEMBIO CO., LTD. (CN) | 2026-02-03 | — | — | US | claimed |
| US-20240317695-A1 | METHOD FOR PREPARING OXETAN-2-YLMETHANAMINE | ACCELA CHEMBIO CO., LTD. (CN) | 2024-09-26 | — | — | US | claimed |
| EP-4194446-A1 | PREPARATION METHOD FOR OXETANE-2-METHYLAMINE | ACCELA CHEMBIO CO., LTD. (CN) | 2023-06-14 | — | — | EP | claimed |
| WO-2023065434-A1 | PREPARATION METHOD FOR OXETANE-2-METHYLAMINE | 韶远科技（上海)有限公司 | 2023-04-27 | — | — | WO | claimed |
| US-12611401-B2 | Combinations comprising benzodioxol as GLP-1R agonists for use in the treatment of NASH/NAFLD and related diseases | PFIZER INC. (US) | 2026-04-28 | — | — | US | disclosed |
| US-12540126-B2 | Method for preparing oxetan-2-ylmethanamine | ACCELA CHEMBIO CO., LTD. (CN) | 2026-02-03 | — | — | US | disclosed |
| EP-4323354-B1 | 2-((4-((S)-2-(4-CHLORO-2-FLUOROPHENYL)-2-METHYLBENZO[D][1,3]DIOXOL-4-YL)PIPERIDIN-1-YL)METHYL)-1-(((S)-OXETAN-2-YL)METHYL)-1H-IMIDAZOLE DERIVATIVES AS ACTIVATORS OF THE GLP1 RECEPTOR FOR THE TREATMENT OF OBESITY | NOVARTIS AG (CH) | 2025-12-17 | — | — | EP | disclosed |
| US-20250340544-A1 | GLP-1 Receptor Agonists and Uses Thereof | PFIZER INC. (US) | 2025-11-06 | — | — | US | disclosed |
| US-20250304577-A1 | TYK2 INHIBITORS | BIOGEN MA INC. | 2025-10-02 | — | — | US | disclosed |
| US-20250270196-A1 | GLP-1 Receptor Agonists and Uses Thereof | PFIZER INC. (US) | 2025-08-28 | — | — | US | disclosed |
| US-20250263402-A1 | BENZIMIDAZOLONE GLP-1 RECEPTOR AGONIST AND USE THEREOF | HANGZHOU ZHONGMEIHUADONG PHARMACEUTICAL CO., LTD. (CN) | 2025-08-21 | — | — | US | disclosed |
| US-12378230-B2 | GLP-1 receptor agonists and uses thereof | PFIZER INC. (US) | 2025-08-05 | — | — | US | disclosed |
| US-20070249663-A1 | PYRAZOLO[1,5-a]PYRIDINES AND MEDICINES CONTAINING THE SAME | HIBI SHIGEKI | 2007-10-25 | — | — | US | disclosed |
| US-7285666-B2 | Pyrazolo[1,5-a] pyridines and medicines containing the same | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2007-10-23 | — | — | US | disclosed |
| EP-1802611-A2 | HETEROCYCLIC DIAMIDE INSECTICIDAL AGENTS | Syngeta Participations AG (CH) | 2007-07-04 | — | — | EP | disclosed |
| US-20060217348-A1 | Pyrazolo[1,5-a] pyridines and medicines containing the same | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2006-09-28 | — | — | US | disclosed |
| US-7091215-B2 | Pyrazolo[1,5-a]pyridines and medicines containing the same | EISAI CO., LTD. (JP) | 2006-08-15 | — | — | US | disclosed |
| WO-2006040113-A2 | HETEROCYCLIC DIAMIDE INSECTICIDAL AGENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2006-04-20 | — | — | WO | disclosed |
| US-20040122039-A1 | Pyrazolo[1,5-a]pyridines and medicines containing the same | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2004-06-24 | — | — | US | disclosed |
| EP-1389618-A1 | PYRAZOLO 1,5-A]PYRIDINES AND MEDICINES CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2004-02-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249663-A1 | PYRAZOLO[1,5-a]PYRIDINES AND MEDICINES CONTAINING THE SAME | NR3C1, NR3C2, NR5A2 | SLC12A2 3825/4885SLC12A5 3082/4885CYP2D6 84/4885 |
| US-20040122039-A1 | Pyrazolo[1,5-a]pyridines and medicines containing the same | XDH, NR3C1, NR5A1 | SLC12A2 3744/4885SLC12A5 2931/4885CYP2D6 40/4885 |
| US-20250263402-A1 | BENZIMIDAZOLONE GLP-1 RECEPTOR AGONIST AND USE THEREOF | GLP1R, GIPR, GCGR | SLC12A2 2959/4885SLC12A5 2742/4885CYP2D6 3620/4885 |
| US-20250304577-A1 | TYK2 INHIBITORS | TYK2, JAK2, JAK1 | SLC12A2 4785/4885SLC12A5 4856/4885CYP2D6 2212/4885 |
| US-20250340544-A1 | GLP-1 Receptor Agonists and Uses Thereof | GLP1R, GIPR, GCGR | SLC12A2 3380/4885SLC12A5 2866/4885CYP2D6 3082/4885 |
| US-12540126-B2 | Method for preparing oxetan-2-ylmethanamine | TH, ALKBH2, ALKBH3 | SLC12A2 1805/4885SLC12A5 3199/4885CYP2D6 877/4885 |
| US-20060217348-A1 | Pyrazolo[1,5-a] pyridines and medicines containing the same | NR3C1, NR3C2, NR5A2 | SLC12A2 3825/4885SLC12A5 3082/4885CYP2D6 84/4885 |
| US-12378230-B2 | GLP-1 receptor agonists and uses thereof | GLP1R, GIPR, GCGR | SLC12A2 3380/4885SLC12A5 2866/4885CYP2D6 3082/4885 |
| US-20250270196-A1 | GLP-1 Receptor Agonists and Uses Thereof | GLP1R, GIPR, GCGR | SLC12A2 3380/4885SLC12A5 2866/4885CYP2D6 3082/4885 |
| US-12611401-B2 | Combinations comprising benzodioxol as GLP-1R agonists for use in the treatment of NASH/NAFLD and related diseases | GLP1R, GCKR, GPR119 | SLC12A2 1375/4885SLC12A5 1596/4885CYP2D6 1784/4885 |
| US-20240317695-A1 | METHOD FOR PREPARING OXETAN-2-YLMETHANAMINE | TH, TET1, TMT1A | SLC12A2 1922/4885SLC12A5 2891/4885CYP2D6 1770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.