Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | APLNR | P35414 | 3/20 | 0.41 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.35 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28574139 | 0.82 | ALPL (0.43) | ALPLCA1CA2CA9DGAT1 | |
| SCHEMBL24576804 | 0.79 | ALPL (0.47) | ALPLCA1CA2CA9DGAT1 | |
| SCHEMBL798868 | 0.77 | ALPL (0.45) | ALPLCA1CA2CA9DGAT1 | |
| SCHEMBL24092455 | 0.77 | APLNR (0.46) | APLNRALDH1A1NPC1CNR1CNR2 | |
| SCHEMBL29778784 | 0.72 | DGAT1 (0.39) | ALPLUCHL1DGAT1SNCAALDH1A1 | |
| SCHEMBL23641247 | 0.72 | DGAT1 (0.39) | ALPLUCHL1DGAT1SNCAALDH1A1 | |
| SCHEMBL2376356 | 0.72 | LMNA (0.47) | APLNRUCHL1CA1CA2CA9 | |
| SCHEMBL21327428 | 0.72 | DGAT1 (0.47) | ALPLUCHL1DGAT1SNCANPC1 | |
| SCHEMBL24696660 | 0.72 | DGAT1 (0.38) | ALPLAPLNRUCHL1DGAT1SNCA | |
| SCHEMBL30039774 | 0.72 | DGAT1 (0.38) | ALPLAPLNRUCHL1DGAT1SNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110785420-B | Oxazepin derivatives as inhibitors of PI 3-kinase activity | 葛兰素史克知识产权开发有限公司 | 2022-04-26 | — | — | CN | disclosed |
| CN-110785420-A | Oxazabenzopyrazole derivatives as inhibitors of PI 3-kinase activity | 葛兰素史克知识产权开发有限公司 | 2020-02-11 | — | — | CN | disclosed |