Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23641247 | 1.00 | DGAT1 (0.39) | DGAT1SNCAUCHL1LMNAMAPT | |
| SCHEMBL24696660 | 0.88 | DGAT1 (0.38) | DGAT1SNCAUCHL1LMNAMAPT | |
| SCHEMBL30039774 | 0.88 | DGAT1 (0.38) | DGAT1SNCAUCHL1LMNAMAPT | |
| SCHEMBL2376356 | 0.82 | LMNA (0.47) | DGAT1SNCAUCHL1LMNAMAPT | |
| SCHEMBL2378626 | 0.80 | DGAT1 (0.46) | DGAT1SNCAUCHL1LMNAMAPT | |
| SCHEMBL21327428 | 0.79 | DGAT1 (0.47) | DGAT1SNCAUCHL1ALPL | |
| SCHEMBL22553942 | 0.77 | UCHL1 (0.38) | DGAT1UCHL1CYP1A2CYP2D6MEN1 | |
| SCHEMBL2377024 | 0.76 | SNCA (0.39) | DGAT1SNCAUCHL1LMNAMAPT | |
| SCHEMBL23641517 | 0.75 | LMNA (0.44) | LMNAMAPTCYP1A2CYP2D6TSHR | |
| SCHEMBL29778801 | 0.75 | LMNA (0.44) | LMNAMAPTCYP1A2CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11976056-B2 | Substituted alkoxypyridinyl indolsulfonamides | UCB PHARMA GMBH (DE) | 2024-05-07 | — | — | US | disclosed |
| EP-4086248-A1 | SUBSTITUTED ALKOXYPYRIDINYL INDOLSULFONAMIDES | UCB Pharma GmbH (DE) | 2022-11-09 | — | — | EP | disclosed |
| EP-3810587-B1 | SUBSTITUTED ALKOXYPYRIDINYL INDOLSULFONAMIDES | UCB PHARMA GMBH (DE) | 2022-08-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11976056-B2 | Substituted alkoxypyridinyl indolsulfonamides | GPR119, GPR17, GPR27 | DGAT1 735/4885SNCA 2078/4885UCHL1 4347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.