SCHEMBL28356161

SCHEMBL28356161

c1cc(N2CCC2)ccc1N1CCC1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.59
MAPT P10636 6/20 0.59
L3MBTL1 Q9Y468 4/20 0.59
KDM4E B2RXH2 4/20 0.59
ALOX15 P16050 3/20 0.59
NPC1 O15118 3/20 0.59
TP53 P04637 3/20 0.59
RAB9A P51151 3/20 0.59
HSD17B10 Q99714 2/20 0.59
MEN1 O00255 2/20 0.59
GAA P10253 2/20 0.59
KMT2A Q03164 2/20 0.59
NPSR1 Q6W5P4 2/20 0.59
USP2 O75604 1/20 0.59
POLB P06746 1/20 0.59
THRB P10828 1/20 0.59
HTT P42858 1/20 0.59
RECQL P46063 1/20 0.59
CHKA P35790 2/20 0.57
TRIM24 O15164 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2174173 0.93 ALDH1A1 (0.67) ALDH1A1MAPTL3MBTL1KDM4EALOX15
Hydrochloric Acid SCHEMBL29475563 0.90 ALDH1A1 (0.71) ALDH1A1MAPTL3MBTL1KDM4EALOX15
SCHEMBL6887590 0.90 ALDH1A1 (0.71) ALDH1A1MAPTL3MBTL1KDM4EALOX15
SCHEMBL16404482 0.86 MAPT (0.64) ALDH1A1MAPTKDM4EALOX15NPC1
SCHEMBL18815076 0.86 LTA4H (0.52) ALDH1A1MAPTL3MBTL1KDM4EALOX15
SCHEMBL23705658 0.86 KMT2A (0.53) ALDH1A1MAPTL3MBTL1KDM4EALOX15
SCHEMBL3043144 0.86 ALDH1A1 (0.57) ALDH1A1MAPTL3MBTL1KDM4EALOX15
SCHEMBL24103508 0.86 SIGMAR1 (0.64) ALDH1A1MAPTL3MBTL1KDM4EALOX15
SCHEMBL18118476 0.86 ADRB1 (0.64) ALDH1A1MAPTL3MBTL1KDM4EALOX15
SCHEMBL1858354 0.86 ALDH1A1 (0.82) ALDH1A1MAPTL3MBTL1KDM4EALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110724128-A Small molecule luminescent material based on 1, 3-naphthyridine (quinazoline), preparation method and application thereof 哈尔滨工业大学 2020-01-24 CN disclosed