SCHEMBL28357635

SCHEMBL28357635

C=C(C)C(c1ccc(C)cc1C)c1ccc(C)cc1C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.45
LMNA P02545 1/20 0.45
CHRM1 P11229 1/20 0.45
SLC6A2 P23975 1/20 0.45
ADRA1A P35348 1/20 0.45
HTR2B P41595 1/20 0.45
TDP1 Q9NUW8 2/20 0.41
TP53 P04637 1/20 0.41
CASR P41180 1/20 0.37
CYP2A6 P11509 2/20 0.37
KMT2A Q03164 1/20 0.37
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
CACNA1G O43497 1/20 0.34
CACNA2D1 P54289 1/20 0.34
CACNA1B Q00975 1/20 0.34
CACNB1 Q02641 1/20 0.34
CACNA1C Q13936 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrogen Peroxide SCHEMBL29099642 0.76 LMNA (0.61) TRPA1LMNACHRM1SLC6A2ADRA1A
SCHEMBL7864024 0.75 MEN1 (0.44) TRPA1LMNACHRM1SLC6A2ADRA1A
SCHEMBL599102 0.75 TRPA1 (0.60) TRPA1LMNACHRM1SLC6A2ADRA1A
SCHEMBL29757164 0.75 TRPA1 (0.60) TRPA1LMNACHRM1SLC6A2ADRA1A
SCHEMBL21995472 0.74 TDP1 (0.44) TRPA1LMNACHRM1SLC6A2ADRA1A
SCHEMBL14571908 0.73 ALDH1A1 (0.42) TRPA1LMNACHRM1SLC6A2ADRA1A
SCHEMBL9685032 0.73 TDP1 (0.48) TRPA1LMNACHRM1SLC6A2ADRA1A
SCHEMBL8756974 0.73 TDP1 (0.48) TRPA1LMNACHRM1SLC6A2ADRA1A
SCHEMBL2235269 0.72 TDP1 (0.46) TRPA1LMNACHRM1SLC6A2ADRA1A
SCHEMBL14677603 0.72 KMT2A (0.48) TDP1KMT2ACACNA1GCACNA2D1CACNA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116003896-A Radiation curable polyolefin formulations 陶氏环球技术有限责任公司 2023-04-25 CN disclosed
CN-110785463-B Radiation-curable polyolefin formulations 陶氏环球技术有限责任公司 2023-03-21 CN disclosed
CN-109790300-B Semi-crystalline polyolefin-based additive masterbatch composition 陶氏环球技术有限责任公司 2022-09-13 CN disclosed
CN-109890878-B Semicrystalline polyolefin additive masterbatch composition 陶氏环球技术有限责任公司 2022-07-08 CN disclosed
CN-109890877-B Additive masterbatch composition based on semicrystalline polyolefins 陶氏环球技术有限责任公司 2022-06-28 CN disclosed
CN-112352013-A Masterbatch with semi-crystalline polyolefin carrier resin 陶氏环球技术有限责任公司 2021-02-09 CN disclosed
CN-111886289-A Masterbatch with semi-crystalline polyolefin carrier resin 陶氏环球技术有限责任公司 2020-11-03 CN disclosed
CN-110785463-A Radiation-curable polyolefin formulations 陶氏环球技术有限责任公司 2020-02-11 CN disclosed