Water

Water

SCHEMBL2835774

O.O=[SiH]O

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL490942 0.93
SCHEMBL28850552 0.86
SCHEMBL9388785 0.62
SCHEMBL4733190 0.57
Water SCHEMBL27382301 0.57
Water SCHEMBL3066495 0.57
Water SCHEMBL27952249 0.51
Water SCHEMBL29273203 0.51
SCHEMBL65500 0.44
SCHEMBL7049 0.44

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9663661-B2 Effect pigments comprising a glass flake substrate ECKART GMBH (DE) 2017-05-30 US claimed
US-8765103-B2 Pearlescent pigments containing cosmetic compositions GLASSFLAKE LIMITED (GB) 2014-07-01 US claimed
US-20100116169-A1 EFFECT PIGMENTS COMPRISING A GLASS FLAKE SUBSTRATE ECKART GMBH (DE) 2010-05-13 US claimed
EP-1977729-B1 Cosmetic compositions containing pearlescent pigments ECKART GMBH (DE) 2010-03-03 EP claimed
US-20100047300-A1 PEARLESCENT PIGMENTS CONTAINING COSMETIC COMPOSITIONS ECKART GMBH (DE) 2010-02-25 US claimed
EP-1980594-B1 Effect pigments comprising a glass flake substrate ECKART GMBH (DE) 2009-06-03 EP claimed
WO-2008122420-A1 EFFECT PIGMENTS COMPRISING A GLASS FLAKE SUBSTRATE ECKART GMBH (DE) 2008-10-16 WO claimed
WO-2008122421-A1 PEARLESCENT PIGMENTS CONTAINING COSMETIC COMPOSITIONS ECKART GMBH (DE) 2008-10-16 WO claimed
EP-1980594-A1 Effect pigments comprising a glass flake substrate Eckart GmbH (DE) 2008-10-15 EP claimed
EP-1977729-A1 Pearlescent pigments containing cosmetic compositions Eckart GmbH (DE) 2008-10-08 EP claimed
EP-1865031-B1 Effect pigments comprising glass flakes having a content of titanium oxide ECKART GMBH (DE) 2008-07-02 EP claimed
WO-2007140897-A1 EFFECT PIGMENTS COMPRISING GLASS FLAKES HAVING A CONTENT OF TITANIUM OXIDE ECKART GMBH (DE) 2007-12-13 WO claimed
EP-1865031-A1 Effect pigments comprising glass flakes having a content of titanium oxide Eckart GmbH &amp; Co. KG (DE) 2007-12-12 EP claimed
US-9663661-B2 Effect pigments comprising a glass flake substrate ECKART GMBH (DE) 2017-05-30 US disclosed
CN-104105665-B Molecular sieve SSZ-87 compositions and synthesis thereof CHEVRON U.S.A. INC. (US) 2015-12-30 CN disclosed
CN-104703916-A Molecular sieve ssz-85 composition of matter and synthesis thereof CHEVRON USA INC 2015-06-10 CN disclosed
CN-101001883-A Flavonoid complexes MERCK PATENT GMBH (DE) 2007-07-18 CN disclosed
CN-1694928-A Non-platelet coating color pigments, method for the production thereof and use thereof MERCK PATENT GMBH (DE) 2005-11-09 CN disclosed
CN-1556774-A Novel hybrid sol for producing abrasion-resistant SiO2 antireflection coatings Ĭ��ר���ɷ����޹�˾ 2004-12-22 CN disclosed
CN-1226875-A Preparation of Y-type faujasite with organic template CHEVRON USA INC (US) 1999-08-25 CN disclosed