SCHEMBL28358758

SCHEMBL28358758

O=C1c2cccc3cccc(c23)C(=O)N1c1ccc[nH]1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.50
KDM4E B2RXH2 5/20 0.50
HPGD P15428 4/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
ERCC1 P07992 1/20 0.50
FEN1 P39748 1/20 0.50
ERCC4 Q92889 1/20 0.50
MEN1 O00255 4/20 0.49
KMT2A Q03164 4/20 0.49
GAA P10253 3/20 0.49
HSD17B10 Q99714 4/20 0.46
CA12 O43570 2/20 0.46
CA9 Q16790 2/20 0.46
MAPT P10636 1/20 0.46
MAPK1 P28482 1/20 0.46
HTT P42858 1/20 0.46
RXFP1 Q9HBX9 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
CYP1B1 Q16678 1/20 0.46
CA1 P00915 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7078045 0.89 PDE6D (0.52) ALDH1A1KDM4EHPGDSMN1; SMN2ERCC1
SCHEMBL2865639 0.83 KMT2A (0.42) ALDH1A1MEN1KMT2ACA12CA9
SCHEMBL24453236 0.75 ERCC1 (0.63) ALDH1A1KDM4EHPGDSMN1; SMN2ERCC1
SCHEMBL20735193 0.74 ALDH1A1 (0.82) ALDH1A1KDM4EHPGDSMN1; SMN2ERCC1
SCHEMBL824432 0.72 ALDH1A1 (0.62) ALDH1A1KDM4EHPGDSMN1; SMN2ERCC1
SCHEMBL28517468 0.72 ERCC1 (0.59) ALDH1A1KDM4EHPGDSMN1; SMN2ERCC1
SCHEMBL862546 0.71 ERCC1 (0.63) ALDH1A1KDM4EHPGDERCC1FEN1
SCHEMBL299841 0.71 ALDH1A1 (0.71) ALDH1A1KDM4EHPGDSMN1; SMN2ERCC1
SCHEMBL28193467 0.70 ALDH1A1 (0.58) ALDH1A1KDM4EHPGDSMN1; SMN2ERCC1
SCHEMBL20735205 0.69 ALDH1A1 (0.74) ALDH1A1KDM4EHPGDSMN1; SMN2ERCC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110832002-B Monomer mixture and curable composition containing same 株式会社大赛璐 2021-03-16 CN disclosed
CN-106459295-B Monomer composition and curable composition containing same 株式会社大赛璐 2020-12-08 CN disclosed
CN-111315798-A Monomer mixture and curable composition containing same 株式会社大赛璐 2020-06-19 CN disclosed
CN-110832002-A Monomer mixture and curable composition containing same 株式会社大赛璐 2020-02-21 CN disclosed
CN-110799569-A Monomer mixture and curable composition containing same 株式会社大赛璐 2020-02-14 CN disclosed
CN-110799568-A Monomer mixture and curable composition containing same 株式会社大赛璐 2020-02-14 CN disclosed