Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28358758 | 0.83 | ALDH1A1 (0.50) | KMT2AMEN1ALDH1A1CA12CA1 | |
| SCHEMBL30267 | 0.77 | CES1 (0.38) | KMT2AMEN1ALDH1A1POLBNR1H2 | |
| SCHEMBL16862997 | 0.76 | POLB (0.50) | KMT2AMEN1ALDH1A1POLBNR1H2 | |
| SCHEMBL7078045 | 0.76 | PDE6D (0.52) | KMT2AMEN1ALDH1A1POLBCA12 | |
| SCHEMBL7135216 | 0.74 | TLR9 (0.44) | FKBP5 | |
| SCHEMBL1232851 | 0.72 | L3MBTL1 (0.37) | KMT2AALDH1A1POLBCA12CA1 | |
| SCHEMBL4649471 | 0.67 | KMT2A (0.78) | KMT2AMEN1ALDH1A1SCN2ACA12 | |
| SCHEMBL4649466 | 0.67 | POLB (0.65) | KMT2AMEN1ALDH1A1POLBNR1H2 | |
| SCHEMBL19370804 | 0.67 | MEN1 (0.51) | KMT2AMEN1SCN2ACA12CA1 | |
| SCHEMBL7406745 | 0.67 | HIPK2 (0.57) | KMT2AMEN1ALDH1A1CASP3HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7740967-B2 | Highly conductive ordered ion exchange membranes | BEN GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) | 2010-06-22 | — | — | US | claimed |
| US-20050238937-A1 | Highly conductive ordered ion exchange membranes | BEN GURION UNIVERSITY (IL) | 2005-10-27 | — | — | US | claimed |
| CN-117229286-A | Aromatic compound, preparation method thereof and application thereof in preparation of estrogen receptor degradation agent | 海创药业股份有限公司 | 2023-12-15 | — | — | CN | disclosed |
| US-11497731-B2 | β-lactamase inhibitor | NATIONAL UNIVERSITY CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEM (JP) | 2022-11-15 | — | — | US | disclosed |
| CN-114181196-A | Compound for inhibiting and degrading PARP enzyme, preparation method and pharmaceutical application thereof | 海思科医药集团股份有限公司 | 2022-03-15 | — | — | CN | disclosed |
| US-20210236463-A1 | beta-LACTAMASE INHIBITOR | NATIONAL UNIVERSITY CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEM (JP) | 2021-08-05 | — | — | US | disclosed |
| EP-3795149-A1 | INHIBITOR & X3B2;-LACTAMASE | National University Corporation Tokai National Higher Education and Research System (JP) | 2021-03-24 | — | — | EP | disclosed |
| EP-2555769-A2 | METHODS FOR TREATING RESPIRATORY VIRAL INFECTION | Celgene Corporation (US) | 2013-02-13 | — | — | EP | disclosed |
| US-7740967-B2 | Highly conductive ordered ion exchange membranes | BEN GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) | 2010-06-22 | — | — | US | disclosed |
| US-7297168-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2007-11-20 | — | — | US | disclosed |
| US-7297168-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2007-11-20 | — | — | US | disclosed |
| US-20050238937-A1 | Highly conductive ordered ion exchange membranes | BEN GURION UNIVERSITY (IL) | 2005-10-27 | — | — | US | disclosed |
| WO-2004005380-A1 | HIGHLY CONDUCTIVE ORDERED ION EXCHANGE MEMBRANES | BEN-GURION UNIVERSITY OF THE NEGEV (IL) | 2004-01-15 | — | — | WO | disclosed |
| EP-0167922-B1 | Pyrrolo [1,2-b] [1,2,5] triazepines, a process and intermediates for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1990-03-28 | — | — | EP | disclosed |
| US-4883794-A | ANALGESICS, ANTICHOLINERGIC AGENTS | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1989-11-28 | — | — | US | disclosed |
| EP-0308912-A2 | Pyrrolo(1,2-b)cinnolines, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1989-03-29 | — | — | EP | disclosed |
| US-4800203-A | ANALGESICS | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1989-01-24 | — | — | US | disclosed |
| US-4588727-A | ANALGESICS, TRANQUILLIZERS, ANTICONVULSANTS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1986-05-13 | — | — | US | disclosed |
| EP-0167922-A2 | Pyrrolo [1,2-b] [1,2,5] triazepines, a process and intermediates for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1986-01-15 | — | — | EP | disclosed |
| US-4517195-A | ANALGESICS, ANXIETY, ANTICONVULSANTS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1985-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210236463-A1 | beta-LACTAMASE INHIBITOR | MGAM, CMBL, MGAM2 | KMT2A 1387/4885MEN1 2730/4885ALDH1A1 683/4885 |
| US-11497731-B2 | β-lactamase inhibitor | MGAM, CMBL, MGAM2 | KMT2A 1187/4885MEN1 2796/4885ALDH1A1 747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.