Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28358902 | 0.83 | MEN1 (0.54) | MEN1KMT2ASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL21046083 | 0.78 | KMT2A (0.59) | MEN1KMT2ASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL13021077 | 0.78 | MEN1 (0.49) | MEN1KMT2ASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL8941930 | 0.76 | ALDH1A1 (0.50) | MEN1KMT2ASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL28021226 | 0.75 | MEN1 (0.58) | MEN1KMT2ASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL4988971 | 0.75 | SMN1; SMN2 (0.61) | MEN1KMT2ASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL27873025 | 0.75 | ALDH1A1 (0.61) | MEN1KMT2ASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL70297 | 0.74 | MEN1 (0.61) | MEN1KMT2ASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL29627490 | 0.74 | MEN1 (0.61) | MEN1KMT2ASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL6849222 | 0.74 | MEN1 (0.71) | MEN1KMT2ASMN1; SMN2GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |
| US-4755509-A | Heterocyclic aldose reductase inhibitors and methods of using them | Carbipem (FR) | 1988-07-05 | — | — | US | disclosed |