Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 1/20 | 0.65 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.65 |
| ▸ | DNPH1 | O43598 | 2/20 | 0.62 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.60 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.60 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.60 |
| ▸ | SRC | P12931 | 2/20 | 0.60 |
| ▸ | DPP4 | P27487 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.60 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.60 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.60 |
| ▸ | GAPDH | P04406 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | STAT6 | P42226 | 1/20 | 0.60 |
| ▸ | PI4KA | P42356 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2835899 | 1.00 | METTL3 (0.65) | METTL3ADORA1DNPH1P2RY1SMN1; SMN2 | |
| SCHEMBL1434032 | 0.91 | ADORA1 (0.72) | METTL3ADORA1DNPH1P2RY1SMN1; SMN2 | |
| SCHEMBL6905464 | 0.91 | ADORA1 (0.72) | METTL3ADORA1DNPH1P2RY1SMN1; SMN2 | |
| SCHEMBL2835155 | 0.85 | ADORA1 (0.67) | ADORA1DNPH1P2RY1SMN1; SMN2P2RY2 | |
| SCHEMBL2835149 | 0.85 | ADORA1 (0.67) | ADORA1DNPH1P2RY1SMN1; SMN2P2RY2 | |
| SCHEMBL22458248 | 0.83 | ADORA1 (0.65) | ADORA1DNPH1P2RY1SMN1; SMN2P2RY2 | |
| SCHEMBL6902192 | 0.83 | ADORA1 (0.62) | METTL3ADORA1DNPH1P2RY1SMN1; SMN2 | |
| SCHEMBL8744184 | 0.82 | ADORA1 (0.66) | ADORA1DNPH1P2RY1SMN1; SMN2P2RY2 | |
| SCHEMBL10997946 | 0.82 | ADORA1 (0.76) | ADORA1DNPH1P2RY1SMN1; SMN2P2RY2 | |
| SCHEMBL6907702 | 0.82 | METTL3 (0.70) | METTL3ADORA1DNPH1P2RY1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100160351-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING HYPERURICEMIA AND RELATED DISORDERS | NUON THERAPEUTICS, INC. (US) | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160351-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING HYPERURICEMIA AND RELATED DISORDERS | XDH, SLC10A1, SLC10A6 | METTL3 2014/4885ADORA1 136/4885DNPH1 1381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.