Hydroxyamine

Hydroxyamine

SCHEMBL2835912

CCCCC(CC)C(O)C(C)N.NO

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SPHK1 Q9NYA1 2/20 0.45
OPRM1 P35372 1/20 0.38
TRPV1 Q8NER1 1/20 0.37
TRPA1 O75762 1/20 0.37
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
TSHR P16473 1/20 0.36
ALDH1A1 P00352 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
TP53 P04637 2/20 0.35
SLC15A1 P46059 1/20 0.35
LMNA P02545 2/20 0.34
CYP2D6 P10635 2/20 0.34
GMNN O75496 1/20 0.34
POLB P06746 1/20 0.34
THPO P40225 1/20 0.34
MTOR P42345 1/20 0.34
BLM P54132 1/20 0.34
KDM4E B2RXH2 1/20 0.34
CYP1A2 P05177 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2840090 0.98 SPHK1 (0.47) SPHK1OPRM1TRPV1TRPA1CA1
SCHEMBL23689971 0.85 SPHK1 (0.47) SPHK1OPRM1TRPV1TRPA1CA1
SCHEMBL11832228 0.82 ALDH1A1 (0.44) CA1CA2TSHRALDH1A1TDP1
SCHEMBL14125822 0.82 ALDH1A1 (0.44) CA1CA2TSHRALDH1A1TDP1
SCHEMBL14561036 0.80 ALDH1A1 (0.39) SPHK1CA1CA2TSHRALDH1A1
SCHEMBL20492541 0.80 OPRM1 (0.46) SPHK1OPRM1TRPV1CA1CA2
SCHEMBL14125514 0.80 ALDH1A1 (0.42) CA1CA2TSHRALDH1A1TDP1
SCHEMBL10894238 0.79 TSHR (0.42) SPHK1TRPV1TRPA1TSHRLMNA
SCHEMBL20779324 0.78 ALDH1A1 (0.38) SPHK1CA1CA2TSHRALDH1A1
SCHEMBL4438548 0.78 ALDH1A1 (0.38) SPHK1CA1CA2TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2117300-B1 AMINOALCOHOL AND BIOCIDE COMPOSITIONS FOR AQUEOUS BASED SYSTEMS ANGUS CHEMICAL (US) 2017-04-19 EP disclosed
US-9034929-B2 Aminoalcohol and biocide compositions for aqueous based systems ANGUS CHEMICAL COMPANY (US) 2015-05-19 US disclosed
US-20120311922-A1 CORROSION AND MICROBIAL CONTROL IN HYDROCARBONACEOUS COMPOSITIONS TINETTI SHEILA M (US) 2012-12-13 US disclosed
EP-2244570-A2 IMPROVED CORROSION AND MICROBIAL CONTROL IN HYDROCARBONACEOUS COMPOSITIONS Dow Global Technologies Inc. (US) 2010-11-03 EP disclosed
US-20100242341-A1 CORROSION AND MICROBIAL CONTROL IN HYDROCARBONACEOUS COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC 2010-09-30 US disclosed
US-20100093736-A1 AMINOALCOHOL AND BIOCIDE COMPOSITIONS FOR AQUEOUS BASED SYSTEMS ANGUS CHEMICAL COMPANY (US) 2010-04-15 US disclosed
EP-2117300-A2 AMINOALCOHOL AND BIOCIDE COMPOSITIONS FOR AQUEOUS BASED SYSTEMS ANGUS CHEMICAL COMPANY (US) 2009-11-18 EP disclosed
WO-2009085552-A2 IMPROVED CORROSION AND MICROBIAL CONTROL IN HYDROCARBONACEOUS COMPOSITIONS DOW GLOBAL TECHNOLOGIES INC. (US) 2009-07-09 WO disclosed
WO-2008088632-A2 AMINOALCOHOL AND BIOCIDE COMPOSITIONS FOR AQUEOUS BASED SYSTEMS ANGUS CHEMICAL COMPANY (US) 2008-07-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100093736-A1 AMINOALCOHOL AND BIOCIDE COMPOSITIONS FOR AQUEOUS BASED SYSTEMS ADH1C, ADH1A, ADH5 SPHK1 3286/4885OPRM1 1130/4885TRPV1 3215/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.