Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 3/20 | 0.31 |
| ▸ | PPARD | Q03181 | 3/20 | 0.31 |
| ▸ | PPARA | Q07869 | 3/20 | 0.31 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.30 |
| ▸ | CCR1 | P32246 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2836856 | 0.94 | NOTUM (0.33) | ALDH1A1HPGDNOTUMP2RX7BRD9 | |
| SCHEMBL2839349 | 0.90 | BRD9 (0.38) | ALDH1A1NOTUMP2RX7BRD9HSD11B1 | |
| SCHEMBL2836068 | 0.88 | P2RX7 (0.43) | ALDH1A1P2RX7 | |
| SCHEMBL2839228 | 0.87 | NOTUM (0.33) | NOTUMP2RX7BRD9HSD11B1 | |
| SCHEMBL2836866 | 0.87 | ALDH1A1 (0.38) | ALDH1A1HPGDDOT1L | |
| SCHEMBL2835974 | 0.86 | P2RX7 (0.43) | ALDH1A1NOTUMP2RX7 | |
| SCHEMBL2833127 | 0.86 | RAB9A (0.39) | ALDH1A1NOTUMP2RX7 | |
| SCHEMBL1573904 | 0.85 | POLB (0.37) | ALDH1A1NOTUM | |
| SCHEMBL2834932 | 0.85 | NOTUM (0.32) | NOTUMP2RX7BRD9 | |
| SCHEMBL2833836 | 0.85 | NOTUM (0.37) | ALDH1A1NOTUMBRD9HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060025591-A1 | New uracils having a herbicidal activity | ISEM S.R.L. (IT) | 2006-02-02 | — | — | US | claimed |
| US-7754880-B2 | Uracils having a herbicidal activity | ISAGRO RICERCA S.R.L. (IT) | 2010-07-13 | — | — | US | disclosed |
| US-20060025591-A1 | New uracils having a herbicidal activity | ISEM S.R.L. (IT) | 2006-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060025591-A1 | New uracils having a herbicidal activity | UNG, DDT, UMPS | ALDH1A1 53/4885HPGD 2001/4885NOTUM 713/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.