Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.58 |
| ▸ | SLC18A3 | Q16572 | 4/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.50 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.50 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | PRCP | P42785 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL54932 | 0.86 | DRD2 (0.63) | DRD2SLC18A3SIGMAR1CARM1PRMT6 | |
| Hydrochloric Acid SCHEMBL1481475 | 0.84 | DRD2 (0.61) | DRD2SLC18A3SIGMAR1CARM1PRMT6 | |
| SCHEMBL27618609 | 0.81 | SLC18A3 (0.54) | DRD2SLC18A3SIGMAR1CARM1PRMT6 | |
| SCHEMBL4034093 | 0.80 | ALDH1A1 (0.57) | DRD2SLC18A3HRH3KCNH2ALDH1A1 | |
| SCHEMBL9910976 | 0.79 | DRD2 (0.56) | DRD2SLC18A3SIGMAR1CARM1PRMT6 | |
| SCHEMBL12669973 | 0.79 | ALDH1A1 (0.54) | DRD2SIGMAR1HDAC3HDAC4HDAC1 | |
| SCHEMBL18857845 | 0.79 | LSS (0.52) | SLC18A3SIGMAR1HRH3HDAC3HDAC4 | |
| SCHEMBL25377908 | 0.77 | QDPR (0.48) | DRD2SLC18A3ALDH1A1 | |
| SCHEMBL31263811 | 0.77 | QDPR (0.48) | DRD2SLC18A3ALDH1A1 | |
| SCHEMBL7722733 | 0.77 | SIGMAR1 (0.75) | DRD2SLC18A3SIGMAR1CARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110840889-A | Construction method of animal model of Parkinson's disease | 江苏省原子医学研究所 | 2020-02-28 | — | — | CN | disclosed |