SCHEMBL2836728

SCHEMBL2836728

C=COB(O)Cc1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
ARG2 P78540 1/20 0.38
TSHR P16473 2/20 0.34
LIPE Q05469 1/20 0.34
MAOB P27338 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
CALM1 P0DP23 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
GAA P10253 1/20 0.32
IDO1 P14902 2/20 0.31
THRB P10828 1/20 0.31
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
AKR1B1 P15121 1/20 0.31
SRC P12931 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27666482 0.73 TSHR (0.40) CA1CA2ARG2TSHRLIPE
SCHEMBL3900187 0.72 CA1 (0.41) CA1CA2ARG2TSHRLIPE
SCHEMBL1356582 0.72 CA1 (0.41) CA1CA2ARG2TSHRLIPE
SCHEMBL3887273 0.71 TSHR (0.46) CA1CA2ARG2TSHRLIPE
SCHEMBL3795674 0.71 LMNA (0.44) CA1CA2SMN1; SMN2CES2CES1
SCHEMBL29171058 0.71 CA1 (0.41) CA1CA2ARG2TSHRTDP1
SCHEMBL23535576 0.69 LIPE (0.39) CA1CA2ARG2TSHRLIPE
SCHEMBL393925 0.68 TRPV6 (0.44) CA1CA2TSHRALDH1A1
SCHEMBL8392410 0.68 ALDH1A1 (0.42) CA1CA2ARG2TSHRLIPE
SCHEMBL28437378 0.68 CA1 (0.57) CA1CA2ARG2TSHRLIPE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100155297-A1 REMOVAL OF NITROGEN COMPOUNDS JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2010-06-24 US claimed
EP-1893723-A1 REMOVAL OF NITROGEN COMPOUNDS JOHNSON MATTHEY PLC (GB) 2008-03-05 EP claimed
WO-2006136862-A1 REMOVAL OF NITROGEN COMPOUNDS JOHNSON MATTHEY PLC (GB) 2006-12-28 WO claimed
US-7083731-B2 Precious metal scavenging from a liquid medium with a functionalised polymer fiber JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2006-08-01 US claimed
US-6906135-B2 Graft copolymers JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2005-06-14 US claimed
EP-1332234-B1 PRECIOUS METAL SCAVENGING FROM A LIQUID MEDIUM WITH A FUNCTIONALISED POLYMER FIBER JOHNSON MATTHEY PLC (GB) 2004-12-29 EP claimed
EP-1337567-B1 GRAFT COPOLYMERS JOHNSON MATTHEY PLC (GB) 2004-09-15 EP claimed
US-20040034117-A1 Graft copolymers JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2004-02-19 US claimed
US-20040026329-A1 Precious metal scavenging from a liquid medium with a functionalised polymer fiber JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2004-02-12 US claimed
EP-1337567-A1 GRAFT COPOLYMERS JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2003-08-27 EP claimed
EP-1332234-A1 PRECIOUS METAL SCAVENGING FROM A LIQUID MEDIUM WITH A FUNCTIONALISED POLYMER FIBER JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2003-08-06 EP claimed
WO-2002036648-A1 GRAFT COPOLYMERS JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2002-05-10 WO claimed
WO-2002033135-A1 PRECIOUS METAL SCAVENGING FROM A LIQUID MEDIUM WITH A FUNCTIONALISED POLYMER FIBER JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2002-04-25 WO claimed
EP-1576896-B1 Catalyst and method of scavenging residual oxygen JOHNSON MATTHEY PLC (GB) 2012-06-13 EP disclosed
US-20100155297-A1 REMOVAL OF NITROGEN COMPOUNDS JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2010-06-24 US disclosed
EP-1893723-A1 REMOVAL OF NITROGEN COMPOUNDS JOHNSON MATTHEY PLC (GB) 2008-03-05 EP disclosed
EP-1307288-A2 GRAFT MODIFIED POLYMER, FIBROUS CATALYST AND USE THEREOF FOR SCAVENGING OXYGEN FROM A SEALED PACKAGE JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2003-05-07 EP disclosed
WO-2002036648-A1 GRAFT COPOLYMERS JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2002-05-10 WO disclosed
WO-2002033135-A1 PRECIOUS METAL SCAVENGING FROM A LIQUID MEDIUM WITH A FUNCTIONALISED POLYMER FIBER JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2002-04-25 WO disclosed
WO-2002011566-A2 GRAFT MODIFIED POLYMER, FIBROUS CATALYST AND USE THEREOF FOR SCAVENGING OXYGEN FROM A SEALED PACKAGE JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2002-02-14 WO disclosed