Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29749250 | 1.00 | MAPT (0.41) | MAPTL3MBTL1CASP3SENP8SENP7 | |
| SCHEMBL3640930 | 0.85 | MAPT (0.46) | MAPTL3MBTL1CASP3SENP8SENP7 | |
| SCHEMBL28901461 | 0.80 | PDE10A (0.47) | MAPTL3MBTL1CASP3SENP8SENP7 | |
| SCHEMBL29749248 | 0.80 | ALDH1A1 (0.59) | MAPTCASP3SENP8SENP7SENP6 | |
| SCHEMBL28368126 | 0.80 | ALDH1A1 (0.59) | MAPTCASP3SENP8SENP7SENP6 | |
| SCHEMBL3258678 | 0.74 | MAPT (0.50) | MAPTL3MBTL1CASP3SENP8SENP7 | |
| SCHEMBL2749466 | 0.73 | ALDH1A1 (0.56) | MAPTL3MBTL1CASP3SENP8SENP7 | |
| SCHEMBL193533 | 0.72 | ALDH1A1 (0.62) | MAPTL3MBTL1KMT2ANPSR1MAPK1 | |
| SCHEMBL21839447 | 0.71 | CASP3 (0.56) | MAPTL3MBTL1CASP3SENP8SENP7 | |
| SCHEMBL28564366 | 0.70 | MAPT (0.39) | MAPTL3MBTL1CASP3SENP8SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110770233-B | Fused bicyclic compound and application thereof in medicine | 广东东阳光药业有限公司 | 2022-07-26 | — | — | CN | disclosed |
| CN-110770233-A | Fused bicyclic compound and application thereof in medicine | 广东东阳光药业有限公司 | 2020-02-07 | — | — | CN | disclosed |