Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL184125 | 0.89 | CA1 (0.58) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8637786 | 0.82 | NFE2L2 (0.49) | NFE2L2NPC1RAB9AMAOBPTGS1 | |
| SCHEMBL7024215 | 0.82 | — | — | |
| SCHEMBL1305285 | 0.82 | CES2 (0.39) | CA1CA2CA7CA9NPC1 | |
| SCHEMBL8298 | 0.82 | — | — | |
| SCHEMBL971237 | 0.81 | CA4 (0.54) | CA12CA1CA2CA7CA9 | |
| SCHEMBL12346502 | 0.81 | ACHE (0.65) | CA12CA1CA2CA7CA9 | |
| SCHEMBL28654012 | 0.76 | CA1 (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL28518750 | 0.76 | ACHE (0.62) | NFE2L2RAB9APTGS1GAAALDH1A1 | |
| SCHEMBL3607576 | 0.75 | NPC1 (0.64) | NFE2L2CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110938092-A | Diaryl phosphine oxide compound containing flame-retardant synergistic element and preparation method thereof | 山东科技大学 | 2020-03-31 | — | — | CN | disclosed |