Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28370565 | 0.82 | NFE2L2 (0.53) | NFE2L2ALDH1A1PTGS1NPC1RAB9A | |
| SCHEMBL31327827 | 0.82 | CES2 (0.43) | NFE2L2NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL2155787 | 0.82 | CES2 (0.43) | NFE2L2NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL2154415 | 0.80 | NFE2L2 (0.42) | NFE2L2NPC1RAB9ATP53MAPT | |
| SCHEMBL971237 | 0.80 | CA4 (0.54) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL184125 | 0.80 | CA1 (0.58) | ALDH1A1KDM4ENPC1RAB9AMAPT | |
| M-Xylene SCHEMBL28323476 | 0.77 | ACHE (0.53) | RELAALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL31327793 | 0.76 | ACHE (0.50) | RELAALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2155309 | 0.76 | ACHE (0.50) | RELAALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2153528 | 0.75 | CA4 (0.48) | ALDH1A1NPC1RAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756848-A | Process for preparing secondary arylphosphine oxides | HOECHST AKTIENGESELLSCHAFT | 1998-05-26 | — | — | US | claimed |
| US-5756848-A | Process for preparing secondary arylphosphine oxides | HOECHST AKTIENGESELLSCHAFT | 1998-05-26 | — | — | US | disclosed |