Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 2/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | ACP3 | P15309 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL184125 | 0.91 | CA1 (0.58) | CA4LTA4HCES2CES1CA1 | |
| SCHEMBL12346502 | 0.83 | ACHE (0.65) | CA1CA2CA12CA7CA9 | |
| SCHEMBL2153528 | 0.82 | CA4 (0.48) | CA4LTA4HCES2CES1CA1 | |
| SCHEMBL28370565 | 0.81 | NFE2L2 (0.53) | CA1CA2CA12CA7CA9 | |
| SCHEMBL821938 | 0.81 | ALDH1A1 (0.33) | CA4CES2CES1CA1CA2 | |
| M-Xylene SCHEMBL28323476 | 0.80 | ACHE (0.53) | CA1CA2CA12CA7CA9 | |
| SCHEMBL8637786 | 0.80 | NFE2L2 (0.49) | NPC1RAB9AALDH1A1GAASMN1; SMN2 | |
| SCHEMBL13583073 | 0.78 | ALDH1A1 (0.35) | CA4CES2CES1CA1CA2 | |
| SCHEMBL1667 | 0.78 | ALDH1A1 (0.35) | CA4CES2CES1CA1CA2 | |
| SCHEMBL2154350 | 0.78 | LTA4H (0.57) | LTA4HCA1CA2CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756848-A | Process for preparing secondary arylphosphine oxides | HOECHST AKTIENGESELLSCHAFT | 1998-05-26 | — | — | US | claimed |
| CN-117417372-A | Preparation method of nickel-catalyzed aromatic phosphine oxide compound | 中南大学 | 2024-01-19 | — | — | CN | disclosed |
| CN-110256489-B | Preparation method of alkyl phosphonyl | 苏州大学 | 2022-03-08 | — | — | CN | disclosed |
| CN-110294776-B | Method for preparing aryl phosphine oxide derivative | 苏州大学 | 2021-12-10 | — | — | CN | disclosed |
| CN-110229187-B | Method for preparing alkyl phosphonyl compound from peroxide | 苏州大学 | 2021-12-10 | — | — | CN | disclosed |
| CN-110218227-B | Method for preparing aryl ketone derivative | 苏州大学 | 2021-12-10 | — | — | CN | disclosed |
| CN-110229188-B | Preparation method of arylmethylphosphonic acid compound | 苏州大学 | 2021-08-27 | — | — | CN | disclosed |
| CN-110938092-A | Diaryl phosphine oxide compound containing flame-retardant synergistic element and preparation method thereof | 山东科技大学 | 2020-03-31 | — | — | CN | disclosed |
| CN-110294776-A | A method of preparing aryl oxide phosphine-derivatives | 苏州大学 | 2019-10-01 | — | — | CN | disclosed |
| CN-110256489-A | A kind of preparation method of alkylphosphines acylate | 苏州大学 | 2019-09-20 | — | — | CN | disclosed |
| CN-102471534-A | Hydroxyphenylphosphine oxide mixtures and their use as flame retardants for epoxy resins | CHEMTURA CORP | 2012-05-23 | — | — | CN | disclosed |
| WO-2011082192-A1 | PHOSPHINYL AMIDINE COMPOUNDS, METAL COMPLEXES, CATALYST SYSTEMS, AND THEIR USE TO OLIGOMERIZE OR POLYMERIZE OLEFINS | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2011-07-07 | — | — | WO | disclosed |
| US-20110015440-A1 | PHOSPHINE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND PEROXIDE SCAVENGER USING THE SAME | FUKUOKA UNIVERSITY (JP) | 2011-01-20 | — | — | US | disclosed |
| CN-1743336-A | Novel hydroxyaryl phosphine oxides,diglycidyl ethers and epoxy compositions, composites and laminates derived therefrom | PABU SERVICES INC (US) | 2006-03-08 | — | — | CN | disclosed |
| CN-1533396-A | Novel hydroxyarylphosphine oxide, glycidyl ether and epoxy compositions and composites and laminates derived therefrom | — | 2004-09-29 | — | — | CN | disclosed |
| CN-1092681-C | Method for producing polycarbonate | UBE INDUSTRIES (JP) | 2002-10-16 | — | — | CN | disclosed |
| EP-0834496-B1 | Preparation of diaryl carbonate | UBE INDUSTRIES (JP) | 2001-08-16 | — | — | EP | disclosed |
| US-5792883-A | Preparation of diaryl carbonate | UBE INDUSTRIES, LTD. (JP) | 1998-08-11 | — | — | US | disclosed |
| US-5756848-A | Process for preparing secondary arylphosphine oxides | HOECHST AKTIENGESELLSCHAFT | 1998-05-26 | — | — | US | disclosed |
| CN-1178806-A | Method for producing polycarbonate | UBE INDUSTRIES (JP) | 1998-04-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110015440-A1 | PHOSPHINE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND PEROXIDE SCAVENGER USING THE SAME | FECH, PRDX5, MTCH2 | CA4 1322/4885LTA4H 3459/4885CES2 2608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.