SCHEMBL28371306

SCHEMBL28371306

CCN(Cc1ccc([N+](=O)[O-])cc1-c1ccc([N+](=O)[O-])cc1)C(=O)OCc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 7/20 0.46
FAAH O00519 1/20 0.45
MGLL Q99685 1/20 0.45
AR P10275 2/20 0.44
CYP2C9 P11712 2/20 0.43
CYP3A4 P08684 1/20 0.43
TBXA2R P21731 1/20 0.43
PTGIR P43119 1/20 0.43
PTGDR Q13258 1/20 0.43
CRHBP P24387 1/20 0.43
CRHR2 Q13324 1/20 0.43
ITGA4 P13612 1/20 0.42
ITGB7 P26010 1/20 0.42
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C19 P33261 1/20 0.41
CYP19A1 P11511 2/20 0.41
CYP11B1 P15538 1/20 0.41
CYP11B2 P19099 1/20 0.41
ALDH1A1 P00352 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28371290 0.84 ALDH1A1 (0.45) PTGDR2FAAHMGLLCYP2C9CYP3A4
SCHEMBL7367394 0.84 CRHBP (0.58) FAAHMGLLARCRHBPCRHR2
SCHEMBL28350135 0.81 ALDH1A1 (0.40) PTGDR2FAAHMGLLARCYP2C9
SCHEMBL28371191 0.81 ALDH1A1 (0.43) PTGDR2FAAHMGLLCYP2C9CYP1A2
SCHEMBL2913482 0.75 RAB9A (0.46) FAAHMGLLCYP3A4CRHBPCRHR2
SCHEMBL135920 0.75 PTGDR2 (0.66) PTGDR2CYP2C9CYP3A4TBXA2RPTGIR
SCHEMBL991783 0.74 ALDH1A1 (0.47) ALDH1A1SMN1; SMN2
SCHEMBL29280745 0.73 ALDH1A1 (0.62) ARCRHBPCRHR2ALDH1A1SMN1; SMN2
SCHEMBL1946099 0.73 PTGDR2 (0.53) PTGDR2CYP2C9CYP3A4TBXA2RPTGIR
SCHEMBL13687190 0.73 LMNA (0.62) PTGDR2MGLLALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110950781-A Novel diamine, polyamic acid, and polyimide 日产化学工业株式会社 2020-04-03 CN disclosed