Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 2/20 | 0.52 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.48 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.48 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.45 |
| ▸ | DGKA | P23743 | 1/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.44 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4451845 | 0.88 | PRKCA (0.56) | PRKCAPRKCEPRKCQPRKCDFAAH | |
| SCHEMBL4458170 | 0.88 | PRKCA (0.56) | PRKCAPRKCEPRKCQPRKCDFAAH | |
| SCHEMBL29168493 | 0.84 | PRKCA (0.50) | PRKCAPRKCEPRKCQPRKCDFAAH | |
| SCHEMBL23923637 | 0.82 | PRKCA (0.50) | PRKCAPRKCEPRKCQPRKCDFAAH | |
| SCHEMBL28997720 | 0.82 | PRKCA (0.51) | PRKCAPRKCEPRKCQPRKCDFAAH | |
| SCHEMBL21014331 | 0.81 | FAAH (0.61) | PRKCAPRKCEPRKCQPRKCDFAAH | |
| SCHEMBL15668671 | 0.80 | PRKCA (0.47) | PRKCAPRKCEPRKCQPRKCDFAAH | |
| SCHEMBL26613661 | 0.80 | LMNA (0.59) | PRKCAPRKCEPRKCQPRKCDMAPT | |
| SCHEMBL20985468 | 0.80 | ALDH1A1 (0.53) | PRKCAPRKCEPRKCQPRKCDFAAH | |
| SCHEMBL992184 | 0.79 | PRKCA (0.54) | PRKCAPRKCEPRKCQPRKCDFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113908288-B | mRNA delivery system and preparation method and application thereof | 深圳市人民医院 | 2023-10-13 | — | — | CN | claimed |
| CN-113372226-B | Lipid molecule, lipid nanoparticle, and preparation methods and application thereof | 深圳市人民医院 | 2023-05-26 | — | — | CN | claimed |
| CN-113786391-B | mRNA delivery system and preparation method and application thereof | 深圳市人民医院 | 2022-07-26 | — | — | CN | claimed |
| CN-113908288-A | mRNA delivery system and preparation method and application thereof | 深圳市人民医院 | 2022-01-11 | — | — | CN | claimed |
| CN-113786391-A | mRNA delivery system and preparation method and application thereof | 深圳市人民医院 | 2021-12-14 | — | — | CN | claimed |
| CN-113372226-A | Lipid molecule, lipid nanoparticle, preparation method and application thereof | 深圳市人民医院 | 2021-09-10 | — | — | CN | claimed |
| CN-113736782-B | Compositions and methods for inhibiting TMPRSS6 gene expression | 阿尔尼拉姆医药品有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-118338907-A | Lipid Nanoparticle (LNP) compositions and methods of using the same | 宾夕法尼亚大学董事会 | 2024-07-12 | — | — | CN | disclosed |
| CN-118317944-A | Acyclic lipids and methods of use thereof | 雷纳嘉德医疗管理公司 | 2024-07-09 | — | — | CN | disclosed |
| CN-118234707-A | Cyclic lipids and methods of use thereof | 雷纳嘉德医疗管理公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-113710811-B | Non-viral modification of T cell gene expression | 精密纳米系统无限责任公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-118043466-A | Substitution of nucleotide bases in self-amplified mRNA | 葛兰素史克生物有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-110381994-B | Nucleoside modified RNA for inducing immune response against Zika virus | 宾夕法尼亚大学理事会 | 2024-05-10 | — | — | CN | disclosed |
| CN-112301031-A | Angiotensinogen (AGT) iRNA compositions and methods of use thereof | 阿尔尼拉姆医药品有限公司 | 2021-02-02 | — | — | CN | disclosed |
| CN-112292395-A | Novel RSV RNA molecules and compositions for vaccination | 库瑞瓦格股份公司 | 2021-01-29 | — | — | CN | disclosed |
| CN-112111492-A | Compositions and methods for inhibiting expression of apolipoprotein C-III (APOC3) gene | 阿尔尼拉姆医药品有限公司 | 2020-12-22 | — | — | CN | disclosed |
| CN-106834291-B | Compositions and methods for inhibiting expression of transthyretin | 阿尔尼拉姆医药品有限公司 | 2020-09-29 | — | — | CN | disclosed |
| CN-111511924-A | RNA sequence modulation | 库瑞瓦格股份公司 | 2020-08-07 | — | — | CN | disclosed |
| CN-111246854-A | Modified MRNA vaccines encoding herpes simplex virus glycoproteins and uses thereof | 宾夕法尼亚大学理事会 | 2020-06-05 | — | — | CN | disclosed |
| CN-110913898-A | Methods of treating subjects having Hepatitis B Virus (HBV) infection | 阿尔尼拉姆医药品有限公司 | 2020-03-24 | — | — | CN | disclosed |