Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 2/20 | 0.56 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.56 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.56 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.56 |
| ▸ | FAAH | O00519 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | DGKA | P23743 | 1/20 | 0.51 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.51 |
| ▸ | TERT | O14746 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4458170 | 1.00 | PRKCA (0.56) | PRKCAPRKCEPRKCQPRKCDFAAH | |
| SCHEMBL23923637 | 0.93 | PRKCA (0.50) | PRKCAPRKCEPRKCQPRKCDFAAH | |
| SCHEMBL21014331 | 0.91 | FAAH (0.61) | PRKCAPRKCEPRKCQPRKCDFAAH | |
| SCHEMBL26613661 | 0.91 | LMNA (0.59) | PRKCAPRKCEPRKCQPRKCDMAPT | |
| SCHEMBL15668671 | 0.91 | PRKCA (0.47) | PRKCAPRKCEPRKCQPRKCDFAAH | |
| SCHEMBL29168493 | 0.90 | PRKCA (0.50) | PRKCAPRKCEPRKCQPRKCDFAAH | |
| SCHEMBL28372017 | 0.88 | PRKCA (0.52) | PRKCAPRKCEPRKCQPRKCDFAAH | |
| SCHEMBL20985468 | 0.87 | ALDH1A1 (0.53) | PRKCAPRKCEPRKCQPRKCDFAAH | |
| SCHEMBL465985 | 0.87 | PRKCA (0.54) | PRKCAPRKCEPRKCQPRKCDFAAH | |
| SCHEMBL992184 | 0.87 | PRKCA (0.54) | PRKCAPRKCEPRKCQPRKCDFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7598421-B2 | Materials for the delivery of biologically-active material to cells | UCL BIOMEDICA PLC (GB) | 2009-10-06 | — | — | US | disclosed |
| US-20050245446-A1 | Materials for the delivery of biologically-active material to cells | NANOGENICS LIMITED (GB) | 2005-11-03 | — | — | US | disclosed |
| EP-1506019-A1 | COMPLEXES FOR THE DELIVERY OF BIOLOGICALLY-ACTIVE MATERIAL TO CELLS | University College London (GB) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003094974-A1 | COMPLEXES FOR THE DELIVERY OF BIOLOGICALLY-ACTIVE MATERIAL TO CELLS | UNIVERSITY COLLEGE LONDON (GB) | 2003-11-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050245446-A1 | Materials for the delivery of biologically-active material to cells | ITGB1, ITGA2B, ITGB2 | PRKCA 4450/4885PRKCE 4616/4885PRKCQ 4095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.