Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.56 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | RIOK2 | Q9BVS4 | 5/20 | 0.50 |
| ▸ | GSK3A | P49840 | 3/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.50 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.50 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 0.50 |
| ▸ | SNRK | Q9NRH2 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23114262 | 0.87 | MEN1 (0.54) | MEN1KMT2ANR1H4NLRP3L3MBTL1 | |
| SCHEMBL24195991 | 0.82 | MEN1 (0.62) | MEN1KMT2ANR1H4NLRP3L3MBTL1 | |
| SCHEMBL28372186 | 0.81 | MEN1 (0.65) | MEN1KMT2ANR1H4NLRP3L3MBTL1 | |
| SCHEMBL1520280 | 0.81 | MEN1 (0.65) | MEN1KMT2ANR1H4NLRP3L3MBTL1 | |
| SCHEMBL31189138 | 0.79 | MEN1 (0.59) | MEN1KMT2ANR1H4NLRP3L3MBTL1 | |
| SCHEMBL5848162 | 0.79 | L3MBTL1 (0.60) | MEN1KMT2ANR1H4NLRP3L3MBTL1 | |
| SCHEMBL2038480 | 0.78 | L3MBTL1 (0.76) | MEN1KMT2ANR1H4NLRP3L3MBTL1 | |
| SCHEMBL21533674 | 0.77 | MEN1 (0.50) | MEN1KMT2ANR1H4NLRP3L3MBTL1 | |
| SCHEMBL9367263 | 0.77 | NR1H4 (0.83) | MEN1KMT2ANR1H4NLRP3L3MBTL1 | |
| SCHEMBL25826478 | 0.77 | MEN1 (0.56) | MEN1KMT2ANR1H4NLRP3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12037307-B2 | — | — | 2024-07-16 | — | — | US | disclosed |
| US-12037307-B2 | — | — | 2024-07-16 | — | — | US | disclosed |
| US-20230227400-A1 | HIGH PURITY 2-NAPHTHYLACETONITRILE AND METHOD FOR PRODUCING SAME | API CORPORATION (JP) | 2023-07-20 | — | — | US | disclosed |
| US-20230227400-A1 | HIGH PURITY 2-NAPHTHYLACETONITRILE AND METHOD FOR PRODUCING SAME | API CORPORATION (JP) | 2023-07-20 | — | — | US | disclosed |
| US-11643386-B2 | High purity 2-naphthylacetonitrile and method for producing same | API CORPORATION (JP) | 2023-05-09 | — | — | US | disclosed |
| US-11643386-B2 | High purity 2-naphthylacetonitrile and method for producing same | API CORPORATION (JP) | 2023-05-09 | — | — | US | disclosed |
| EP-3950664-A1 | HIGH PURITY 2-NAPHTHYLACETONITRILE AND METHOD FOR PRODUCING SAME | API Corporation (JP) | 2022-02-09 | — | — | EP | disclosed |
| US-20220009880-A1 | HIGH PURITY 2-NAPHTHYLACETONITRILE AND METHOD FOR PRODUCING SAME | API CORPORATION (JP) | 2022-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11643386-B2 | High purity 2-naphthylacetonitrile and method for producing same | SULT2A1, GNPAT, SULT1A1 | MEN1 3099/4885KMT2A 845/4885NR1H4 2778/4885 |
| US-20220009880-A1 | HIGH PURITY 2-NAPHTHYLACETONITRILE AND METHOD FOR PRODUCING SAME | SULT2A1, GNPAT, SULT1A1 | MEN1 3099/4885KMT2A 845/4885NR1H4 2778/4885 |
| US-12037307-B2 | — | SULT2A1, SULT1A1, GNPAT | MEN1 3267/4885KMT2A 1267/4885NR1H4 2158/4885 |
| US-20230227400-A1 | HIGH PURITY 2-NAPHTHYLACETONITRILE AND METHOD FOR PRODUCING SAME | NAT1, CYP2J2, NQO1 | MEN1 597/4885KMT2A 2320/4885NR1H4 3594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.