Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.35 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2839306 | 0.91 | ALDH1A1 (0.45) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL4869823 | 0.75 | KMT2A (0.48) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL4698664 | 0.73 | ALDH1A1 (0.35) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL254935 | 0.71 | KMT2A (0.50) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL6223415 | 0.64 | ALDH3A1 (0.53) | ALDH1A1HPGDMEN1KMT2ALMNA | |
| SCHEMBL19949959 | 0.63 | MAPT (0.39) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL339129 | 0.62 | DYRK1A (0.61) | ALDH1A1HSD17B10TDP1DYRK1ADYRK2 | |
| SCHEMBL2416319 | 0.62 | ALDH1A1 (0.53) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL6499823 | 0.61 | TRIM24 (0.32) | ALDH1A1SMN1; SMN2KDM4EALDH1A3MAOB | |
| SCHEMBL30186040 | 0.60 | ALDH1A1 (0.53) | ALDH1A1MAPTHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046190-A2 | TRICYCLIC ALDEHYDES AND C,H ACIDIC COMPOUNDS | HENKEL AG & CO. KGAA (DE) | 2010-04-29 | — | — | WO | claimed |
| WO-2010046190-A2 | TRICYCLIC ALDEHYDES AND C,H ACIDIC COMPOUNDS | HENKEL AG & CO. KGAA (DE) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046190-A2 | TRICYCLIC ALDEHYDES AND C,H ACIDIC COMPOUNDS | HENKEL AG & CO. KGAA (DE) | 2010-04-29 | — | — | WO | disclosed |