Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10887108 | 0.97 | ATM (0.44) | ATMHCAR2ALDH1A1MAPTMEN1 | |
| SCHEMBL28980704 | 0.86 | ATM (0.38) | ATMHCAR2ALDH1A1MAPTRAB9A | |
| SCHEMBL349288 | 0.82 | ATM (0.47) | ATMHCAR2ALDH1A1MAPTRAB9A | |
| SCHEMBL19888880 | 0.82 | BBOX1 (0.46) | ATMHCAR2MEN1POLBKMT2A | |
| SCHEMBL16628436 | 0.81 | ATM (0.46) | ATMHCAR2ALDH1A1MAPTRAB9A | |
| Ammonia Solution, Strong SCHEMBL16628574 | 0.81 | ATM (0.46) | ATMHCAR2ALDH1A1MAPTRAB9A | |
| SCHEMBL16628614 | 0.81 | ATM (0.46) | ATMHCAR2ALDH1A1MAPTRAB9A | |
| SCHEMBL16628566 | 0.81 | ATM (0.46) | ATMHCAR2ALDH1A1MAPTRAB9A | |
| SCHEMBL1334437 | 0.81 | ATM (0.46) | ATMHCAR2ALDH1A1MAPTRAB9A | |
| SCHEMBL2058381 | 0.81 | ATM (0.46) | ATMHCAR2ALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110809598-B | Hydrogel, use thereof, and method for producing same | 积水化成品工业株式会社 | 2022-07-12 | — | — | CN | disclosed |
| CN-110809598-A | Hydrogel, use thereof, and method for producing same | 积水化成品工业株式会社 | 2020-02-18 | — | — | CN | disclosed |