Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.32 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8607795 | 0.73 | GLA (0.50) | LMNATP53L3MBTL1MEN1ALDH1A1 | |
| SCHEMBL28198306 | 0.69 | SMN1; SMN2 (0.37) | LMNATHRBMEN1ALDH1A1KMT2A | |
| SCHEMBL27700737 | 0.67 | LMNA (0.40) | LMNATHRBTP53L3MBTL1ALDH1A1 | |
| SCHEMBL25545471 | 0.67 | LMNA (0.52) | LMNATHRBTP53L3MBTL1MEN1 | |
| SCHEMBL25545477 | 0.65 | L3MBTL1 (0.69) | LMNATHRBTP53L3MBTL1ALDH1A1 | |
| SCHEMBL23214501 | 0.64 | GRK6 (0.41) | ALDH1A1TSHR | |
| SCHEMBL18711314 | 0.64 | SPR (0.44) | MEN1KMT2AATM | |
| SCHEMBL25545519 | 0.64 | LMNA (0.52) | LMNATHRBTP53L3MBTL1ATM | |
| SCHEMBL25601807 | 0.62 | LMNA (0.42) | LMNATHRBTP53ALDH1A1HPSE | |
| SCHEMBL20851567 | 0.62 | F10 (0.41) | LMNAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107522661-B | Preparation method of 2-mercapto-1-alkyl imidazole | 浦拉司科技（上海）有限责任公司 | 2020-01-07 | — | — | CN | disclosed |
| CN-107522661-A | A kind of preparation method of the alkyl imidazole of 2 sulfydryl 1 | 浦拉司科技（上海）有限责任公司 | 2017-12-29 | — | — | CN | disclosed |