Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14624712 | 0.76 | ALDH1A1 (0.60) | ALDH1A1POLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28198306 | 0.76 | SMN1; SMN2 (0.37) | ALDH1A1POLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28127725 | 0.74 | — | — | |
| SCHEMBL2980873 | 0.74 | — | — | |
| SCHEMBL8938457 | 0.73 | LPO (0.48) | GLAALOX15ALDH1A1POLBNPC1 | |
| SCHEMBL9805593 | 0.73 | ALDH1A1 (0.61) | ALDH1A1POLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28384357 | 0.73 | LMNA (0.43) | GLAALOX15ALDH1A1NPC1RAB9A | |
| SCHEMBL10913815 | 0.72 | LPO (0.43) | GLAALOX15ALDH1A1POLBNPC1 | |
| SCHEMBL7258739 | 0.72 | ALDH1A1 (0.39) | GLAALOX15ALDH1A1POLBNPC1 | |
| SCHEMBL3764555 | 0.72 | RAB9A (0.60) | ALDH1A1POLBNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107522661-B | Preparation method of 2-mercapto-1-alkyl imidazole | 浦拉司科技（上海）有限责任公司 | 2020-01-07 | — | — | CN | disclosed |
| CN-107522661-A | A kind of preparation method of the alkyl imidazole of 2 sulfydryl 1 | 浦拉司科技（上海）有限责任公司 | 2017-12-29 | — | — | CN | disclosed |
| US-5747513-A | HYPOTENSIVE AGENTS, HEART FAILURE AND CEREBROVASCULAR INSUFFICIENCY | ZAMBON GROUP, S.P.A. (IT) | 1998-05-05 | — | — | US | disclosed |