Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28383417 | 0.80 | ALKBH5 (0.42) | MEN1USP2KMT2AKEAP1NFE2L2 | |
| SCHEMBL12918296 | 0.76 | CYP1A2 (0.41) | USP2CYP1A2CYP2A6CDK2PSMB8 | |
| SCHEMBL1092203 | 0.75 | PTGS2 (0.43) | MEN1KMT2ACYP1A2CYP2A6CDK2 | |
| SCHEMBL30564423 | 0.74 | CYP1A2 (0.39) | CYP1A2CYP2A6CDK2PSMB8PRMT5 | |
| SCHEMBL20588288 | 0.70 | PNMT (0.46) | CYP1A2CYP2A6CDK2PRMT5PTPN11 | |
| SCHEMBL838056 | 0.70 | ALDH1A1 (0.54) | MEN1KMT2ACYP1A2CYP2A6KDM4E | |
| SCHEMBL18857084 | 0.69 | GPR84 (0.57) | MEN1KMT2ACDK2KDM4EALDH1A1 | |
| SCHEMBL25669450 | 0.69 | MEN1 (0.39) | MEN1USP2KMT2AKEAP1NFE2L2 | |
| SCHEMBL22450706 | 0.69 | BRD4 (0.54) | KMT2ACDK2ALDH1A1POLBNR4A2 | |
| SCHEMBL28831936 | 0.69 | CDK2 (0.47) | MEN1KMT2ACDK2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111032654-A | Bicyclic heteroaromatic urea or carbamate compounds for use in therapy | 欧洲分子生物学实验室 | 2020-04-17 | — | — | CN | disclosed |