SCHEMBL28387482

SCHEMBL28387482

CCCCCCCCCCCCCCCCC(OCC)(OOc1ccccc1CCCCCCCC)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.41
THRB P10828 1/20 0.41
PPARA Q07869 3/20 0.39
PPARG P37231 2/20 0.38
LIPG Q9Y5X9 1/20 0.38
ALOX5 P09917 1/20 0.37
PTGS2 P35354 1/20 0.37
CYSLTR2 Q9NS75 3/20 0.35
CYSLTR1 Q9Y271 3/20 0.35
LTB4R Q15722 1/20 0.34
LTB4R2 Q9NPC1 1/20 0.34
BID P55957 3/20 0.33
MCL1 Q07820 3/20 0.33
BCL2L1 Q07817 2/20 0.33
BAK1 Q16611 2/20 0.33
KAT8 Q9H7Z6 2/20 0.33
EP300 Q09472 1/20 0.33
KAT2A Q92830 1/20 0.33
KAT2B Q92831 1/20 0.33
KAT5 Q92993 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3972776 0.78 SIGMAR1 (0.37) CNR1CNR2
SCHEMBL6755985 0.78 LTA4H (0.37) CNR1CNR2
SCHEMBL8067579 0.72 THRA (0.52) THRATHRBPPARAPPARGLIPG
SCHEMBL28834518 0.72 PPARA (0.48) THRATHRBPPARAPPARGLIPG
SCHEMBL28952534 0.72 PPARA (0.48) THRATHRBPPARAPPARGLIPG
SCHEMBL6897404 0.72 THRA (0.55) THRATHRBPPARAPPARGLIPG
SCHEMBL7994685 0.72 THRA (0.55) THRATHRBPPARAPPARGLIPG
SCHEMBL27488333 0.71 ALOX5 (0.54) THRATHRBPPARAPPARGLIPG
SCHEMBL659863 0.70 THRA (0.50) THRATHRBPPARAPPARGLIPG
SCHEMBL659864 0.70 THRA (0.50) THRATHRBPPARAPPARGLIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111033777-A Dielectric layer comprising copolymer with mesogenic units PPG工业俄亥俄公司 2020-04-17 CN disclosed