SCHEMBL28389409

SCHEMBL28389409

C=CCN1CC(P(=O)(O)O)c2ccccc21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
PRCP P42785 2/20 0.35
ACP3 P15309 1/20 0.34
HTR2B P41595 1/20 0.33
GAA P10253 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
PTK2B Q14289 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
HTR1A P08908 2/20 0.32
OPRD1 P41143 1/20 0.32
OPRM1 P35372 1/20 0.32
DRD1 P21728 1/20 0.32
DRD5 P21918 1/20 0.32
TSHR P16473 1/20 0.32
NOTUM Q6P988 1/20 0.31
TEAD1 P28347 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6684665 0.74 PRCP (0.45) ALDH1A1PRCPSIGMAR1HTR1AOPRD1
SCHEMBL28473102 0.67 HTR1A (0.38) ALDH1A1PRCPSIGMAR1HTR1AOPRM1
SCHEMBL2571298 0.65 ADRA1D (0.42) ALDH1A1PRCPGAASMN1; SMN2L3MBTL1
SCHEMBL19949789 0.65 ADRA1D (0.42) ALDH1A1PRCPGAAL3MBTL1HTR1A
SCHEMBL7862113 0.65 SMN1; SMN2 (0.35) ALDH1A1PRCPSMN1; SMN2NOTUM
SCHEMBL1519268 0.65 MCL1 (0.50) ALDH1A1NOTUM
SCHEMBL11050039 0.64 ALDH1A1 (0.37) ALDH1A1HTR2BGAATSHR
SCHEMBL11139910 0.64 SIRT1 (0.38) ALDH1A1HTR2BGAAL3MBTL1
SCHEMBL28736922 0.63 BRD4 (0.45) ALDH1A1PRCPGAAOPRD1DRD1
SCHEMBL28736925 0.63 BRD4 (0.45) ALDH1A1PRCPGAAOPRD1DRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108383875-B Silver-catalyzed 3-phosphonomethylindoline and preparation method thereof 昆明学院 2020-04-28 CN disclosed